TY - JOUR
T1 - Information hierarchies optimize patient-centered solutions
AU - Waldman, S. A.
AU - Terzic, A.
PY - 2013/1
Y1 - 2013/1
N2 - Enabling science and information technologies has catalyzed a surge of biological, clinical, demographic, health services, and comparative- effectiveness data. While accelerating the deconvolution of complex pathophysiological, medical, social, and environmental networks and systems, these platforms have produced informational quanta devoid of contextualization. Therapeutic innovation is thus now challenged with moving beyond knowledge generation and curation to integrated solution-seeking paradigms that organize functionally related information, producing system-level insights into health and disease for optimized patient-centered outcomes. This annual issue on therapeutics innovations highlights emerging considerations for the generation and hierarchical organization of scientific and clinical information and its translation to advancing next-generation disease management.
AB - Enabling science and information technologies has catalyzed a surge of biological, clinical, demographic, health services, and comparative- effectiveness data. While accelerating the deconvolution of complex pathophysiological, medical, social, and environmental networks and systems, these platforms have produced informational quanta devoid of contextualization. Therapeutic innovation is thus now challenged with moving beyond knowledge generation and curation to integrated solution-seeking paradigms that organize functionally related information, producing system-level insights into health and disease for optimized patient-centered outcomes. This annual issue on therapeutics innovations highlights emerging considerations for the generation and hierarchical organization of scientific and clinical information and its translation to advancing next-generation disease management.
UR - http://www.scopus.com/inward/record.url?scp=84871333580&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84871333580&partnerID=8YFLogxK
U2 - 10.1038/clpt.2012.208
DO - 10.1038/clpt.2012.208
M3 - Review article
C2 - 23241831
AN - SCOPUS:84871333580
SN - 0009-9236
VL - 93
SP - 3
EP - 7
JO - Clinical pharmacology and therapeutics
JF - Clinical pharmacology and therapeutics
IS - 1
ER -