Abstract
Objective To (1) define population-based incidence of knee Osteochondritis dissecans (OCD) lesions using the population of Olmsted County, (2) examine trends over time, and (3) evaluate rate of surgical management over time. Method Study population included 302 individuals who were diagnosed with knee OCD lesions between January 1, 1976 and December 31, 2014. Complete medical records were reviewed to extract injury and treatment details. Age- and gender-specific incidence rates were calculated and adjusted to the 2010 US population. Poisson regression analyses were performed to examine incidence and surgery trends by age, gender, and calendar period. Results Overall age- and gender-adjusted incidence annual incidence of knee OCD lesions was 6.09 per 100,000 person-years. The incidence was significantly higher (P < 0.001) in males (8.82, 95% CI 7.63 to 10.00 per 100,000) compared to females (3.32, 95% CI 2.61 to 4.04 per 100,000). Age- and gender-specific incidence was highest in both males and females in the 11–15 years old at 39.06 and 16.15 per 100,000, respectively. In males aged 11–15 years, OCD incidence increased significantly over the study period from 20.68 in 1976–1985 to 48.16 in 2006–2014 (per 100,000). Conclusions Overall age- and gender-adjusted annual incidence of knee OCD lesions in the Olmsted Country Population was 6.09 per 100,000 person-years with a significantly higher incidence in males compared to females. The highest incidence for both males and females occurred between the ages 11–15 years. Trends indicate increasing OCD incidence in younger males and decreasing surgical management in females over the last decade.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1663-1671 |
| Number of pages | 9 |
| Journal | Osteoarthritis and Cartilage |
| Volume | 25 |
| Issue number | 10 |
| DOIs | |
| State | Published - Oct 1 2017 |
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Keywords
- Epidemiology
- Incidence
- Knee
- OCD
- Osteochondritis dissecans
ASJC Scopus subject areas
- Rheumatology
- Biomedical Engineering
- Orthopedics and Sports Medicine
Cite this
Incidence of symptomatic osteochondritis dissecans lesions of the knee : a population-based study in Olmsted County. / Pareek, A.; Sanders, T. L.; Wu, I. T.; Larson, D. R.; Saris, D. B.F.; Krych, Aaron.
In: Osteoarthritis and Cartilage, Vol. 25, No. 10, 01.10.2017, p. 1663-1671.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Incidence of symptomatic osteochondritis dissecans lesions of the knee
T2 - a population-based study in Olmsted County
AU - Pareek, A.
AU - Sanders, T. L.
AU - Wu, I. T.
AU - Larson, D. R.
AU - Saris, D. B.F.
AU - Krych, Aaron
PY - 2017/10/1
Y1 - 2017/10/1
N2 - Objective To (1) define population-based incidence of knee Osteochondritis dissecans (OCD) lesions using the population of Olmsted County, (2) examine trends over time, and (3) evaluate rate of surgical management over time. Method Study population included 302 individuals who were diagnosed with knee OCD lesions between January 1, 1976 and December 31, 2014. Complete medical records were reviewed to extract injury and treatment details. Age- and gender-specific incidence rates were calculated and adjusted to the 2010 US population. Poisson regression analyses were performed to examine incidence and surgery trends by age, gender, and calendar period. Results Overall age- and gender-adjusted incidence annual incidence of knee OCD lesions was 6.09 per 100,000 person-years. The incidence was significantly higher (P < 0.001) in males (8.82, 95% CI 7.63 to 10.00 per 100,000) compared to females (3.32, 95% CI 2.61 to 4.04 per 100,000). Age- and gender-specific incidence was highest in both males and females in the 11–15 years old at 39.06 and 16.15 per 100,000, respectively. In males aged 11–15 years, OCD incidence increased significantly over the study period from 20.68 in 1976–1985 to 48.16 in 2006–2014 (per 100,000). Conclusions Overall age- and gender-adjusted annual incidence of knee OCD lesions in the Olmsted Country Population was 6.09 per 100,000 person-years with a significantly higher incidence in males compared to females. The highest incidence for both males and females occurred between the ages 11–15 years. Trends indicate increasing OCD incidence in younger males and decreasing surgical management in females over the last decade.
AB - Objective To (1) define population-based incidence of knee Osteochondritis dissecans (OCD) lesions using the population of Olmsted County, (2) examine trends over time, and (3) evaluate rate of surgical management over time. Method Study population included 302 individuals who were diagnosed with knee OCD lesions between January 1, 1976 and December 31, 2014. Complete medical records were reviewed to extract injury and treatment details. Age- and gender-specific incidence rates were calculated and adjusted to the 2010 US population. Poisson regression analyses were performed to examine incidence and surgery trends by age, gender, and calendar period. Results Overall age- and gender-adjusted incidence annual incidence of knee OCD lesions was 6.09 per 100,000 person-years. The incidence was significantly higher (P < 0.001) in males (8.82, 95% CI 7.63 to 10.00 per 100,000) compared to females (3.32, 95% CI 2.61 to 4.04 per 100,000). Age- and gender-specific incidence was highest in both males and females in the 11–15 years old at 39.06 and 16.15 per 100,000, respectively. In males aged 11–15 years, OCD incidence increased significantly over the study period from 20.68 in 1976–1985 to 48.16 in 2006–2014 (per 100,000). Conclusions Overall age- and gender-adjusted annual incidence of knee OCD lesions in the Olmsted Country Population was 6.09 per 100,000 person-years with a significantly higher incidence in males compared to females. The highest incidence for both males and females occurred between the ages 11–15 years. Trends indicate increasing OCD incidence in younger males and decreasing surgical management in females over the last decade.
KW - Epidemiology
KW - Incidence
KW - Knee
KW - OCD
KW - Osteochondritis dissecans
UR - http://www.scopus.com/inward/record.url?scp=85025802149&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85025802149&partnerID=8YFLogxK
U2 - 10.1016/j.joca.2017.07.005
DO - 10.1016/j.joca.2017.07.005
M3 - Article
C2 - 28711583
AN - SCOPUS:85025802149
VL - 25
SP - 1663
EP - 1671
JO - Osteoarthritis and Cartilage
JF - Osteoarthritis and Cartilage
SN - 1063-4584
IS - 10
ER -