Incidence of symptomatic osteochondritis dissecans lesions of the knee: a population-based study in Olmsted County

A. Pareek, T. L. Sanders, I. T. Wu, D. R. Larson, D. B.F. Saris, Aaron Krych

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Objective To (1) define population-based incidence of knee Osteochondritis dissecans (OCD) lesions using the population of Olmsted County, (2) examine trends over time, and (3) evaluate rate of surgical management over time. Method Study population included 302 individuals who were diagnosed with knee OCD lesions between January 1, 1976 and December 31, 2014. Complete medical records were reviewed to extract injury and treatment details. Age- and gender-specific incidence rates were calculated and adjusted to the 2010 US population. Poisson regression analyses were performed to examine incidence and surgery trends by age, gender, and calendar period. Results Overall age- and gender-adjusted incidence annual incidence of knee OCD lesions was 6.09 per 100,000 person-years. The incidence was significantly higher (P < 0.001) in males (8.82, 95% CI 7.63 to 10.00 per 100,000) compared to females (3.32, 95% CI 2.61 to 4.04 per 100,000). Age- and gender-specific incidence was highest in both males and females in the 11–15 years old at 39.06 and 16.15 per 100,000, respectively. In males aged 11–15 years, OCD incidence increased significantly over the study period from 20.68 in 1976–1985 to 48.16 in 2006–2014 (per 100,000). Conclusions Overall age- and gender-adjusted annual incidence of knee OCD lesions in the Olmsted Country Population was 6.09 per 100,000 person-years with a significantly higher incidence in males compared to females. The highest incidence for both males and females occurred between the ages 11–15 years. Trends indicate increasing OCD incidence in younger males and decreasing surgical management in females over the last decade.

Original languageEnglish (US)
Pages (from-to)1663-1671
Number of pages9
JournalOsteoarthritis and Cartilage
Volume25
Issue number10
DOIs
StatePublished - Oct 1 2017

Keywords

  • Epidemiology
  • Incidence
  • Knee
  • OCD
  • Osteochondritis dissecans

ASJC Scopus subject areas

  • Rheumatology
  • Biomedical Engineering
  • Orthopedics and Sports Medicine

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