Improving the outcome of patients with leptomeningeal cancer: new clinical trials and experimental therapies.

Kurt A. Jaeckle

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

Current therapy for leptomeningeal metastases is predominantly palliative. In an effort to improve disease control and patient outcome, new strategies are being developed to target the cerebrospinal space. These include new intrathecal formulations of systemic chemotherapy as well as the development of radiolabeled immunoconjugates and antitumor antibodies. Furthermore, there is debate as to the optimal strategy of drug delivery for leptomeningeal tumor.

Original languageEnglish (US)
Pages (from-to)181-193
Number of pages13
JournalCancer treatment and research
Volume125
DOIs
StatePublished - 2005

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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