Impact of prior nicotine replacement therapy on smoking cessation efficacy

Michael J. Durcan; Jonathan White; Douglas E. Jorenby; Michael C. Fiore; Stephen I. Rennard; Scott J. Leischow; Mitchell A. Nides; John A. Ascher; J. Andrew Johnston

doi:10.5993/AJHB.26.3.6

Impact of prior nicotine replacement therapy on smoking cessation efficacy

Michael J. Durcan, Jonathan White, Douglas E. Jorenby, Michael C. Fiore, Stephen I. Rennard, Scott J. Leischow, Mitchell A. Nides, John A. Ascher, J. Andrew Johnston

Quantitative Health Sciences

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Objective: To examine previous use of nicotine replacement therapy (NRT) on the smoking-cessation efficacy of bupropion sustained release (SR). Methods: Secondary analysis of a parallel-group, randomized, double-blind, placebo-controlled study. Smokers who had, based on self-report, no previous history of NRT (N=453) or who had used NRT at least once (N=440) were randomized to receive placebo, bupropion SR, nicotine transdermal system (NTS), or a combination of bupropion SR and NTS. Results: Bupropion SR showed similar efficacy in participants with or without previous use of NRT. Conclusion: Bupropion SR is effective in promoting smoking abstinence regardless of prior NRT use.

Original language	English (US)
Pages (from-to)	213-220
Number of pages	8
Journal	American Journal of Health Behavior
Volume	26
Issue number	3
DOIs	https://doi.org/10.5993/AJHB.26.3.6
State	Published - 2002

ASJC Scopus subject areas

Health(social science)
Social Psychology
Public Health, Environmental and Occupational Health

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title = "Impact of prior nicotine replacement therapy on smoking cessation efficacy",

abstract = "Objective: To examine previous use of nicotine replacement therapy (NRT) on the smoking-cessation efficacy of bupropion sustained release (SR). Methods: Secondary analysis of a parallel-group, randomized, double-blind, placebo-controlled study. Smokers who had, based on self-report, no previous history of NRT (N=453) or who had used NRT at least once (N=440) were randomized to receive placebo, bupropion SR, nicotine transdermal system (NTS), or a combination of bupropion SR and NTS. Results: Bupropion SR showed similar efficacy in participants with or without previous use of NRT. Conclusion: Bupropion SR is effective in promoting smoking abstinence regardless of prior NRT use.",

author = "Durcan, {Michael J.} and Jonathan White and Jorenby, {Douglas E.} and Fiore, {Michael C.} and Rennard, {Stephen I.} and Leischow, {Scott J.} and Nides, {Mitchell A.} and Ascher, {John A.} and Johnston, {J. Andrew}",

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T1 - Impact of prior nicotine replacement therapy on smoking cessation efficacy

AU - Durcan, Michael J.

AU - White, Jonathan

AU - Jorenby, Douglas E.

AU - Fiore, Michael C.

AU - Rennard, Stephen I.

AU - Leischow, Scott J.

AU - Nides, Mitchell A.

AU - Ascher, John A.

AU - Johnston, J. Andrew

PY - 2002

Y1 - 2002

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Impact of prior nicotine replacement therapy on smoking cessation efficacy

Abstract

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