Immunologic diseases, anti-inflammatory drugs, and Parkinson disease: A case-control study

J. H. Bower; D. M. Maraganore; B. J. Peterson; J. E. Ahlskog; W. A. Rocca

doi:10.1212/01.wnl.0000227906.99570.cc

Immunologic diseases, anti-inflammatory drugs, and Parkinson disease: A case-control study

J. H. Bower, D. M. Maraganore, B. J. Peterson, J. E. Ahlskog, W. A. Rocca

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Abstract

The authors studied the association of markers of inflammation with the later development of Parkinson disease (PD) using a case-control design (196 cases and 196 matched controls). The frequency of diseases of immediate-type hypersensitivity was significantly higher in cases than controls. In addition, cases used anti-inflammatory agents less frequently than controls (nonsignificant trend). The results may support the hypothesis that there is an inflammatory component in the pathogenesis of PD.

Original language	English (US)
Pages (from-to)	494-496
Number of pages	3
Journal	Neurology
Volume	67
Issue number	3
DOIs	https://doi.org/10.1212/01.wnl.0000227906.99570.cc
State	Published - Aug 2006

ASJC Scopus subject areas

Clinical Neurology

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title = "Immunologic diseases, anti-inflammatory drugs, and Parkinson disease: A case-control study",

abstract = "The authors studied the association of markers of inflammation with the later development of Parkinson disease (PD) using a case-control design (196 cases and 196 matched controls). The frequency of diseases of immediate-type hypersensitivity was significantly higher in cases than controls. In addition, cases used anti-inflammatory agents less frequently than controls (nonsignificant trend). The results may support the hypothesis that there is an inflammatory component in the pathogenesis of PD.",

author = "Bower, {J. H.} and Maraganore, {D. M.} and Peterson, {B. J.} and Ahlskog, {J. E.} and Rocca, {W. A.}",

note = "Funding Information: Supported by NIH grants R01 NS33978 and R01 ES10751 and made possible by the Rochester Epidemiology Project (grant R01 AR30582). ",

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AU - Peterson, B. J.

AU - Ahlskog, J. E.

AU - Rocca, W. A.

N1 - Funding Information: Supported by NIH grants R01 NS33978 and R01 ES10751 and made possible by the Rochester Epidemiology Project (grant R01 AR30582).

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N2 - The authors studied the association of markers of inflammation with the later development of Parkinson disease (PD) using a case-control design (196 cases and 196 matched controls). The frequency of diseases of immediate-type hypersensitivity was significantly higher in cases than controls. In addition, cases used anti-inflammatory agents less frequently than controls (nonsignificant trend). The results may support the hypothesis that there is an inflammatory component in the pathogenesis of PD.

AB - The authors studied the association of markers of inflammation with the later development of Parkinson disease (PD) using a case-control design (196 cases and 196 matched controls). The frequency of diseases of immediate-type hypersensitivity was significantly higher in cases than controls. In addition, cases used anti-inflammatory agents less frequently than controls (nonsignificant trend). The results may support the hypothesis that there is an inflammatory component in the pathogenesis of PD.

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Immunologic diseases, anti-inflammatory drugs, and Parkinson disease: A case-control study

Abstract

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