Imaging patterns and focal lesions in fatty liver

a pictorial review

Sudhakar K Venkatesh, Tiffany Hennedige, Geoffrey B. Johnson, David M. Hough, Joel Garland Fletcher

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Non-alcoholic fatty liver disease is the most common cause of chronic liver disease and affects nearly one-third of US population. With the increasing trend of obesity in the population, associated fatty change in the liver will be a common feature observed in imaging studies. Fatty liver causes changes in liver parenchyma appearance on imaging modalities including ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) and may affect the imaging characteristics of focal liver lesions (FLLs). The imaging characteristics of FLLs were classically described in a non-fatty liver. In addition, focal fatty change and focal fat sparing may also simulate FLLs. Knowledge of characteristic patterns of fatty change in the liver (diffuse, geographical, focal, subcapsular, and perivascular) and their impact on the detection and characterization of FLL is therefore important. In general, fatty change may improve detection of FLLs on MRI using fat suppression sequences, but may reduce sensitivity on a single-phase (portal venous) CT and conventional ultrasound. In patients with fatty liver, MRI is generally superior to ultrasound and CT for detection and characterization of FLL. In this pictorial essay, we describe the imaging patterns of fatty change in the liver and its effect on detection and characterization of FLLs on ultrasound, CT, MRI, and PET.

Original languageEnglish (US)
Pages (from-to)1-19
Number of pages19
JournalAbdominal Radiology
DOIs
StateAccepted/In press - Dec 20 2016

Fingerprint

Fatty Liver
Liver
Tomography
Magnetic Resonance Imaging
Fats
Population
Liver Diseases
Chronic Disease
Obesity

Keywords

  • CT
  • Fatty liver
  • Focal liver lesions
  • Hepatic steatosis
  • MRI
  • PET
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology
  • Radiological and Ultrasound Technology

Cite this

Imaging patterns and focal lesions in fatty liver : a pictorial review. / Venkatesh, Sudhakar K; Hennedige, Tiffany; Johnson, Geoffrey B.; Hough, David M.; Fletcher, Joel Garland.

In: Abdominal Radiology, 20.12.2016, p. 1-19.

Research output: Contribution to journalArticle

Venkatesh, Sudhakar K ; Hennedige, Tiffany ; Johnson, Geoffrey B. ; Hough, David M. ; Fletcher, Joel Garland. / Imaging patterns and focal lesions in fatty liver : a pictorial review. In: Abdominal Radiology. 2016 ; pp. 1-19.
@article{0dc4dae598254dcb9be5c8755e007414,
title = "Imaging patterns and focal lesions in fatty liver: a pictorial review",
abstract = "Non-alcoholic fatty liver disease is the most common cause of chronic liver disease and affects nearly one-third of US population. With the increasing trend of obesity in the population, associated fatty change in the liver will be a common feature observed in imaging studies. Fatty liver causes changes in liver parenchyma appearance on imaging modalities including ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) and may affect the imaging characteristics of focal liver lesions (FLLs). The imaging characteristics of FLLs were classically described in a non-fatty liver. In addition, focal fatty change and focal fat sparing may also simulate FLLs. Knowledge of characteristic patterns of fatty change in the liver (diffuse, geographical, focal, subcapsular, and perivascular) and their impact on the detection and characterization of FLL is therefore important. In general, fatty change may improve detection of FLLs on MRI using fat suppression sequences, but may reduce sensitivity on a single-phase (portal venous) CT and conventional ultrasound. In patients with fatty liver, MRI is generally superior to ultrasound and CT for detection and characterization of FLL. In this pictorial essay, we describe the imaging patterns of fatty change in the liver and its effect on detection and characterization of FLLs on ultrasound, CT, MRI, and PET.",
keywords = "CT, Fatty liver, Focal liver lesions, Hepatic steatosis, MRI, PET, Ultrasound",
author = "Venkatesh, {Sudhakar K} and Tiffany Hennedige and Johnson, {Geoffrey B.} and Hough, {David M.} and Fletcher, {Joel Garland}",
year = "2016",
month = "12",
day = "20",
doi = "10.1007/s00261-016-1002-6",
language = "English (US)",
pages = "1--19",
journal = "Abdominal Radiology",
issn = "2366-004X",
publisher = "Springer New York",

}

TY - JOUR

T1 - Imaging patterns and focal lesions in fatty liver

T2 - a pictorial review

AU - Venkatesh, Sudhakar K

AU - Hennedige, Tiffany

AU - Johnson, Geoffrey B.

AU - Hough, David M.

AU - Fletcher, Joel Garland

PY - 2016/12/20

Y1 - 2016/12/20

N2 - Non-alcoholic fatty liver disease is the most common cause of chronic liver disease and affects nearly one-third of US population. With the increasing trend of obesity in the population, associated fatty change in the liver will be a common feature observed in imaging studies. Fatty liver causes changes in liver parenchyma appearance on imaging modalities including ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) and may affect the imaging characteristics of focal liver lesions (FLLs). The imaging characteristics of FLLs were classically described in a non-fatty liver. In addition, focal fatty change and focal fat sparing may also simulate FLLs. Knowledge of characteristic patterns of fatty change in the liver (diffuse, geographical, focal, subcapsular, and perivascular) and their impact on the detection and characterization of FLL is therefore important. In general, fatty change may improve detection of FLLs on MRI using fat suppression sequences, but may reduce sensitivity on a single-phase (portal venous) CT and conventional ultrasound. In patients with fatty liver, MRI is generally superior to ultrasound and CT for detection and characterization of FLL. In this pictorial essay, we describe the imaging patterns of fatty change in the liver and its effect on detection and characterization of FLLs on ultrasound, CT, MRI, and PET.

AB - Non-alcoholic fatty liver disease is the most common cause of chronic liver disease and affects nearly one-third of US population. With the increasing trend of obesity in the population, associated fatty change in the liver will be a common feature observed in imaging studies. Fatty liver causes changes in liver parenchyma appearance on imaging modalities including ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) and may affect the imaging characteristics of focal liver lesions (FLLs). The imaging characteristics of FLLs were classically described in a non-fatty liver. In addition, focal fatty change and focal fat sparing may also simulate FLLs. Knowledge of characteristic patterns of fatty change in the liver (diffuse, geographical, focal, subcapsular, and perivascular) and their impact on the detection and characterization of FLL is therefore important. In general, fatty change may improve detection of FLLs on MRI using fat suppression sequences, but may reduce sensitivity on a single-phase (portal venous) CT and conventional ultrasound. In patients with fatty liver, MRI is generally superior to ultrasound and CT for detection and characterization of FLL. In this pictorial essay, we describe the imaging patterns of fatty change in the liver and its effect on detection and characterization of FLLs on ultrasound, CT, MRI, and PET.

KW - CT

KW - Fatty liver

KW - Focal liver lesions

KW - Hepatic steatosis

KW - MRI

KW - PET

KW - Ultrasound

UR - http://www.scopus.com/inward/record.url?scp=85006786109&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85006786109&partnerID=8YFLogxK

U2 - 10.1007/s00261-016-1002-6

DO - 10.1007/s00261-016-1002-6

M3 - Article

SP - 1

EP - 19

JO - Abdominal Radiology

JF - Abdominal Radiology

SN - 2366-004X

ER -