Imaging features of carcinoid tumors metastatic to the breast

Katrina Nesta Glazebrook, Katie N. Jones, Christina A. Dilaveri, Kyle Perry, Carol Reynolds

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The objective of this study was to describe the imaging findings of carcinoid tumors metastatic to the breast, with pathologic and clinical correlations. We searched our surgical database for cases of pathologically proven carcinoid tumors metastatic to the breast from October 1, 2000, to May 31, 2010. Of the approximate 10,000 breast biopsies identified, 7000 had malignant findings. Ten cases of metastatic carcinoid (0.1% of all malignancies), all with imaging studies available for review, were included in the study. All patients were women and had their primary carcinoid in the gastrointestinal tract (n = 9) or lung (n = 1). One patient presented with a palpable breast mass and no history of carcinoid tumor; an ileal carcinoid was discovered after the pathologic diagnosis of metastatic carcinoid was established. In the breast, tumors presented as solitary lesions in half the cases. Metastases to the breast typically presented as circumscribed masses mammographically and as hypoechoic circumscribed masses ultrasonographically; some showed increased through-transmission and increased vascularity with color Doppler evaluation. Five patients had octreotide scans; of these, 4 had increased focal activity in the region of metastasis within the breast. Six patients underwent computed tomography. Without contrast, nodular masses were observed; with contrast, the masses showed rapid enhancement during arterial phase imaging. Magnetic resonance imaging (n = 4) also showed rapid enhancement and washout kinetics after contrast administration. Recognition of carcinoid metastases to the breast in patients with known or occult primary carcinoid tumors is important to avoid unnecessary treatment for primary breast cancer.

Original languageEnglish (US)
Pages (from-to)109-115
Number of pages7
JournalCancer Imaging
Volume11
Issue number1
DOIs
StatePublished - 2011

Fingerprint

Carcinoid Tumor
Breast
Neoplasm Metastasis
Octreotide
Gastrointestinal Tract
Neoplasms
Color
Tomography
Magnetic Resonance Imaging
Databases
Breast Neoplasms
Biopsy
Lung

Keywords

  • Biopsy
  • Pathology
  • Treatment

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Imaging features of carcinoid tumors metastatic to the breast. / Glazebrook, Katrina Nesta; Jones, Katie N.; Dilaveri, Christina A.; Perry, Kyle; Reynolds, Carol.

In: Cancer Imaging, Vol. 11, No. 1, 2011, p. 109-115.

Research output: Contribution to journalArticle

Glazebrook, KN, Jones, KN, Dilaveri, CA, Perry, K & Reynolds, C 2011, 'Imaging features of carcinoid tumors metastatic to the breast', Cancer Imaging, vol. 11, no. 1, pp. 109-115. https://doi.org/10.1102/1470-7330.2011.0018
Glazebrook, Katrina Nesta ; Jones, Katie N. ; Dilaveri, Christina A. ; Perry, Kyle ; Reynolds, Carol. / Imaging features of carcinoid tumors metastatic to the breast. In: Cancer Imaging. 2011 ; Vol. 11, No. 1. pp. 109-115.
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