Imaging and Quantification of Cardiac Sarcoidosis

Mohamed Y. Elwazir, John P. Bois, Omar F. Abou Ezzeddine, Panithaya Chareonthaitawee

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Cardiac sarcoidosis (CS) refers to the increasingly recognized cardiac involvement of an incompletely understood systemic disease entity-sarcoidosis. Endomyocardial biopsy can provide definitive diagnosis but is limited by its invasiveness and poor sensitivity. In the absence of a reliable gold standard, a combination of clinical, electrocardiographic, imaging, and histologic criteria are relied upon to provide probabilistic diagnosis. Within the last few years, societal documents have included advanced cardiovascular imaging modalities, 18F-FDG-PET/CT and cardiac magnetic resonance in their diagnostic algorithms. The current article provides a review of the imaging modalities used for screening and detection of CS, highlighting the principal findings of each with a specific focus on quantification, whenever applicable, and concluding with a proposed approach to the imaging of patients with suspected CS.

Original languageEnglish (US)
Pages (from-to)283-294
Number of pages12
JournalSeminars in Nuclear Medicine
Volume50
Issue number4
DOIs
StatePublished - Jul 2020

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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