Image-based structure-to-function correlation of tissue engineering scaffolds

Rajagopalan Srinivasan, Richard A. Robb

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Tissue engineering is an interdisciplinary effort aimed at the repair and regeneration of biological tissues through the application and control of cells, porous scaffolds and growth factors. While there is a general intuitive consensus on the influence of scaffold architecture on the regeneration of tissues, the specific magnitude of these architectural indices are loosely defined. This paper investigates the application of image-based metrology and traditional wet-lab studies to understand cellular responses and phenotype expression to scaffold microarchitecture. Unraveling the symbiotic structure-to-function relationship of scaffolds might have profound implications leading to the deployment of benchside tissue analogs to the clinical bedside.

Original languageEnglish (US)
Title of host publicationProceedings - 2009 IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, ISBI 2009
Pages594-597
Number of pages4
DOIs
StatePublished - Nov 17 2009
Event2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009 - Boston, MA, United States
Duration: Jun 28 2009Jul 1 2009

Publication series

NameProceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009

Other

Other2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009
CountryUnited States
CityBoston, MA
Period6/28/097/1/09

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Keywords

  • Image processing
  • Porous media
  • Scaffolds
  • Tissue engineering

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

Cite this

Srinivasan, R., & Robb, R. A. (2009). Image-based structure-to-function correlation of tissue engineering scaffolds. In Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009 (pp. 594-597). [5193117] (Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009). https://doi.org/10.1109/ISBI.2009.5193117