Image-based structure-to-function correlation of tissue engineering scaffolds

Rajagopalan Srinivasan; Richard A. Robb

doi:10.1109/ISBI.2009.5193117

Image-based structure-to-function correlation of tissue engineering scaffolds

Rajagopalan Srinivasan, Richard A. Robb

Physiology & Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

Tissue engineering is an interdisciplinary effort aimed at the repair and regeneration of biological tissues through the application and control of cells, porous scaffolds and growth factors. While there is a general intuitive consensus on the influence of scaffold architecture on the regeneration of tissues, the specific magnitude of these architectural indices are loosely defined. This paper investigates the application of image-based metrology and traditional wet-lab studies to understand cellular responses and phenotype expression to scaffold microarchitecture. Unraveling the symbiotic structure-to-function relationship of scaffolds might have profound implications leading to the deployment of benchside tissue analogs to the clinical bedside.

Original language	English (US)
Title of host publication	Proceedings - 2009 IEEE International Symposium on Biomedical Imaging
Subtitle of host publication	From Nano to Macro, ISBI 2009
Pages	594-597
Number of pages	4
DOIs	https://doi.org/10.1109/ISBI.2009.5193117
State	Published - 2009
Event	2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009 - Boston, MA, United States Duration: Jun 28 2009 → Jul 1 2009

Publication series

Name	Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009

Other

Other	2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009
Country/Territory	United States
City	Boston, MA
Period	6/28/09 → 7/1/09

Keywords

Image processing
Porous media
Scaffolds
Tissue engineering

ASJC Scopus subject areas

Biomedical Engineering
Radiology Nuclear Medicine and imaging

Access to Document

10.1109/ISBI.2009.5193117

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Srinivasan, R., & Robb, R. A. (2009). Image-based structure-to-function correlation of tissue engineering scaffolds. In Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009 (pp. 594-597). Article 5193117 (Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009). https://doi.org/10.1109/ISBI.2009.5193117

Image-based structure-to-function correlation of tissue engineering scaffolds. / Srinivasan, Rajagopalan; Robb, Richard A.
Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009. 2009. p. 594-597 5193117 (Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Srinivasan, R & Robb, RA 2009, Image-based structure-to-function correlation of tissue engineering scaffolds. in Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009., 5193117, Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009, pp. 594-597, 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009, Boston, MA, United States, 6/28/09. https://doi.org/10.1109/ISBI.2009.5193117

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abstract = "Tissue engineering is an interdisciplinary effort aimed at the repair and regeneration of biological tissues through the application and control of cells, porous scaffolds and growth factors. While there is a general intuitive consensus on the influence of scaffold architecture on the regeneration of tissues, the specific magnitude of these architectural indices are loosely defined. This paper investigates the application of image-based metrology and traditional wet-lab studies to understand cellular responses and phenotype expression to scaffold microarchitecture. Unraveling the symbiotic structure-to-function relationship of scaffolds might have profound implications leading to the deployment of benchside tissue analogs to the clinical bedside.",

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Image-based structure-to-function correlation of tissue engineering scaffolds

Abstract

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Other

Keywords

ASJC Scopus subject areas

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