IgG4-related tubulointerstitial nephritis

Lynn D. Cornell

Research output: Contribution to journalComment/debate

26 Scopus citations

Abstract

Tubulointerstitial nephritis (TIN) is a disease pattern with heterogeneous causes. Recently a specific subtype of autoimmune TIN, IgG4-related TIN, has been identified that is part of systemic IgG4-related disease/ autoimmune pancreatitis. On biopsy, this TIN shows an IgG4 plasma cell-rich infiltrate, akin to the pancreatic tissue findings in autoimmune pancreatitis, and may show tubulointerstitial immune complex deposits. Notably, some cases may be mass-forming. Recognition of this specific type of TIN can guide appropriate patient therapy.

Original languageEnglish (US)
Pages (from-to)951-953
Number of pages3
JournalKidney international
Volume78
Issue number10
DOIs
StatePublished - Nov 1 2010

ASJC Scopus subject areas

  • Nephrology

Fingerprint Dive into the research topics of 'IgG4-related tubulointerstitial nephritis'. Together they form a unique fingerprint.

  • Cite this