Abstract
In this report, we describe the first case of a patient with an IgG4-related paratesticular pseudotumor. He had histologically proven autoimmune pancreatitis, then later developed a scrotal mass. The orchiectomy specimen revealed that this was a paratesticular pseudotumor with histopathologic and immunohistochemistry findings characteristic of IgG4-related disease. Paratesticular pseudotumors are uncommon causes of intrascrotal masses and have an unexplained pathogenesis. A variety of genitourinary manifestations of IgG4-related disease including IgG4-related tubulointerstitial nephritis, IgG4-related ureteral pseudotumors, and IgG4-related prostatitis has been previously reported. The current case highlights the need to have a high index of suspicion for IgG4 -tissue infiltration in patients with known autoimmune pancreatitis, particularly those with a pseudotumor.
Original language | English (US) |
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Pages (from-to) | 2084-2087 |
Number of pages | 4 |
Journal | Human Pathology |
Volume | 43 |
Issue number | 11 |
DOIs | |
State | Published - Nov 2012 |
Keywords
- Autoimmune pancreatitis
- IgG4-related disease
- Paratesticular
- Pseudotumor
ASJC Scopus subject areas
- Pathology and Forensic Medicine