Ideomotor apraxia in Huntington's disease

P. A. Shelton, David S Knopman

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

The pattern of movement errors in ideomotor apraxia suggests an abnormality in selection and sequencing of component movements. Individuals with Huntington's disease were evaluated prospectively for the presence of apraxia, and aspects of motor and cognitive function were correlated with apraxic errors. Based on a conservative apraxia rating, ideomotor apraxia occurred in three (33%) of nine patients with a mean duration of disease of 10.4 years. Only two (22%) individuals made no apraxic errors, however, and the group as a whole made apraxic errors in 26% of movements. Apraxia was associated with errors in imitation of nonsymbolic movements butnot with errors in recognition of gestures. It correlated significantly with duration of disease and with progressive abnormalities of posture but not with other individual aspects of elementary motor or cognitive function. These associations indicate that apraxia in Huntington's disease may be due primarily to involvement of subcortical motor structures rather than cerebral cortex.

Original languageEnglish (US)
Pages (from-to)35-41
Number of pages7
JournalArchives of Neurology
Volume48
Issue number1
StatePublished - 1991
Externally publishedYes

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Ideomotor Apraxia
Apraxias
Huntington Disease
Cognition
Gestures
Posture
Cerebral Cortex
Apraxia

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Ideomotor apraxia in Huntington's disease. / Shelton, P. A.; Knopman, David S.

In: Archives of Neurology, Vol. 48, No. 1, 1991, p. 35-41.

Research output: Contribution to journalArticle

Shelton, P. A. ; Knopman, David S. / Ideomotor apraxia in Huntington's disease. In: Archives of Neurology. 1991 ; Vol. 48, No. 1. pp. 35-41.
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