Identification of the cloned gene for the murine transplantation antigen H-2K(b) by hybridization with synthetic oligonucleotides

D. H. Schulze, L. R. Pease, Y. Obata, S. G. Nathenson, A. A. Reyes, S. Ikuta, R. B. Wallace

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

The H-2K(b) gene is a member of the large major histocompatibility complex class I gene family. Since many members of this family cross-hybridize with class I cDNA probes, the cloned H-2K(b) gene was identified by hybridization with specific oligonucleotide probes. This clone was definitively shown to encode the H-2K(b) polypeptide by partial DNA sequencing and by serological and tryptic peptide analyses of the expressed product.

Original languageEnglish (US)
Pages (from-to)750-755
Number of pages6
JournalUnknown Journal
Volume3
Issue number4
DOIs
StatePublished - Jan 1 1983

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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