ICSH recommendations for the measurement of Haemoglobin A 2

A. D. Stephens, M. Angastiniotis, E. Baysal, V. Chan, S. Fucharoen, P. C. Giordano, J. D. Hoyer, A. Mosca, B. Wild

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

Abstract

Although DNA analysis is needed for characterization of the mutations that cause β-thalassaemia, measurement of the Hb A 2 is essential for the routine identification of people who are carriers of β-thalassaemia. The methods of quantitating Hb A 2 are described together with pitfalls in undertaking these laboratory tests with particular emphasis on automated high-performance liquid chromatography and capillary electrophoresis.

Original languageEnglish (US)
Pages (from-to)1-13
Number of pages13
JournalInternational Journal of Laboratory Hematology
Volume34
Issue number1
DOIs
StatePublished - Feb 2012

Keywords

  • Capillary electrophoresis
  • HPLC
  • Haemoglobinopathy
  • Hb A
  • Recommended methods
  • Thalassaemia

ASJC Scopus subject areas

  • Hematology
  • Clinical Biochemistry
  • Biochemistry, medical

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