ICSH recommendations for the measurement of Haemoglobin A 2

A. D. Stephens; M. Angastiniotis; E. Baysal; V. Chan; S. Fucharoen; P. C. Giordano; J. D. Hoyer; A. Mosca; B. Wild

doi:10.1111/j.1751-553X.2011.01368.x

ICSH recommendations for the measurement of Haemoglobin A ₂

A. D. Stephens, M. Angastiniotis, E. Baysal, V. Chan, S. Fucharoen, P. C. Giordano, J. D. Hoyer, A. Mosca, B. Wild

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

Although DNA analysis is needed for characterization of the mutations that cause β-thalassaemia, measurement of the Hb A ₂ is essential for the routine identification of people who are carriers of β-thalassaemia. The methods of quantitating Hb A ₂ are described together with pitfalls in undertaking these laboratory tests with particular emphasis on automated high-performance liquid chromatography and capillary electrophoresis.

Original language	English (US)
Pages (from-to)	1-13
Number of pages	13
Journal	International Journal of Laboratory Hematology
Volume	34
Issue number	1
DOIs	https://doi.org/10.1111/j.1751-553X.2011.01368.x
State	Published - Feb 2012

Keywords

Capillary electrophoresis
HPLC
Haemoglobinopathy
Hb A
Recommended methods
Thalassaemia

ASJC Scopus subject areas

Hematology
Clinical Biochemistry
Biochemistry, medical

Access to Document

10.1111/j.1751-553X.2011.01368.x

Cite this

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title = "ICSH recommendations for the measurement of Haemoglobin A 2 ",

abstract = "Although DNA analysis is needed for characterization of the mutations that cause β-thalassaemia, measurement of the Hb A 2 is essential for the routine identification of people who are carriers of β-thalassaemia. The methods of quantitating Hb A 2 are described together with pitfalls in undertaking these laboratory tests with particular emphasis on automated high-performance liquid chromatography and capillary electrophoresis.",

keywords = "Capillary electrophoresis, HPLC, Haemoglobinopathy, Hb A, Recommended methods, Thalassaemia",

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AU - Angastiniotis, M.

AU - Baysal, E.

AU - Chan, V.

AU - Fucharoen, S.

AU - Giordano, P. C.

AU - Hoyer, J. D.

AU - Mosca, A.

AU - Wild, B.

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KW - Haemoglobinopathy

KW - Hb A

KW - Recommended methods

KW - Thalassaemia

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