ICSH recommendations for the measurement of Haemoglobin A 2

A. D. Stephens, M. Angastiniotis, E. Baysal, V. Chan, S. Fucharoen, P. C. Giordano, James Hoyer, A. Mosca, B. Wild

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Although DNA analysis is needed for characterization of the mutations that cause β-thalassaemia, measurement of the Hb A 2 is essential for the routine identification of people who are carriers of β-thalassaemia. The methods of quantitating Hb A 2 are described together with pitfalls in undertaking these laboratory tests with particular emphasis on automated high-performance liquid chromatography and capillary electrophoresis.

Original languageEnglish (US)
Pages (from-to)1-13
Number of pages13
JournalInternational Journal of Laboratory Hematology
Volume34
Issue number1
DOIs
StatePublished - Feb 1 2012
Externally publishedYes

Fingerprint

Hemoglobin A
Capillary electrophoresis
Thalassemia
High performance liquid chromatography
varespladib methyl
DNA
Capillary Electrophoresis
High Pressure Liquid Chromatography
Mutation

Keywords

  • Capillary electrophoresis
  • Haemoglobinopathy
  • Hb A
  • HPLC
  • Recommended methods
  • Thalassaemia

ASJC Scopus subject areas

  • Hematology
  • Clinical Biochemistry
  • Biochemistry, medical

Cite this

Stephens, A. D., Angastiniotis, M., Baysal, E., Chan, V., Fucharoen, S., Giordano, P. C., ... Wild, B. (2012). ICSH recommendations for the measurement of Haemoglobin A 2 International Journal of Laboratory Hematology, 34(1), 1-13. https://doi.org/10.1111/j.1751-553X.2011.01368.x

ICSH recommendations for the measurement of Haemoglobin A 2 . / Stephens, A. D.; Angastiniotis, M.; Baysal, E.; Chan, V.; Fucharoen, S.; Giordano, P. C.; Hoyer, James; Mosca, A.; Wild, B.

In: International Journal of Laboratory Hematology, Vol. 34, No. 1, 01.02.2012, p. 1-13.

Research output: Contribution to journalArticle

Stephens, AD, Angastiniotis, M, Baysal, E, Chan, V, Fucharoen, S, Giordano, PC, Hoyer, J, Mosca, A & Wild, B 2012, 'ICSH recommendations for the measurement of Haemoglobin A 2 ', International Journal of Laboratory Hematology, vol. 34, no. 1, pp. 1-13. https://doi.org/10.1111/j.1751-553X.2011.01368.x
Stephens AD, Angastiniotis M, Baysal E, Chan V, Fucharoen S, Giordano PC et al. ICSH recommendations for the measurement of Haemoglobin A 2 International Journal of Laboratory Hematology. 2012 Feb 1;34(1):1-13. https://doi.org/10.1111/j.1751-553X.2011.01368.x
Stephens, A. D. ; Angastiniotis, M. ; Baysal, E. ; Chan, V. ; Fucharoen, S. ; Giordano, P. C. ; Hoyer, James ; Mosca, A. ; Wild, B. / ICSH recommendations for the measurement of Haemoglobin A 2 In: International Journal of Laboratory Hematology. 2012 ; Vol. 34, No. 1. pp. 1-13.
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