Iatrogenic seizures during intracranial EEG monitoring

Julie A. Khoury, Katherine H. Noe, Joseph F. Drazkowski, Joseph I. Sirven, Richard S. Zimmerman

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Cerebral edema with declining neurologic status is a known complication of intracranial electroencephalography (EEG) monitoring. The frequency and consequences of iatrogenic edema that is not clinically evident are presently poorly defined. We investigated the potential for intracranial electrodes to cause subclinical cerebral edema, and for such edema to cause iatrogenic seizures. In a retrospective review of 33 adults who had head magnetic resonance imaging (MRI) while undergoing epilepsy surgery evaluation with intracranial EEG, 28% (6 of 21) depth electrode implantations had subclinical vasogenic edema. Of these, 50% (3 of 6) had nonhabitual electrographic seizures that appear to result from iatrogenic edema. No long-term adverse sequelae were noted, however, if unrecognized, iatrogenic seizures could lead to unnecessary exclusion from definitive surgical intervention for refractory epilepsy.

Original languageEnglish (US)
JournalEpilepsia
Volume52
Issue number10
DOIs
StatePublished - Oct 2011

Fingerprint

Edema
Seizures
Brain Edema
Epilepsy
Electrodes
Nervous System
Head
Magnetic Resonance Imaging
Electrocorticography

Keywords

  • Epilepsy
  • Intracranial electroencephalography
  • MRI
  • Seizures

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Khoury, J. A., Noe, K. H., Drazkowski, J. F., Sirven, J. I., & Zimmerman, R. S. (2011). Iatrogenic seizures during intracranial EEG monitoring. Epilepsia, 52(10). https://doi.org/10.1111/j.1528-1167.2011.03161.x

Iatrogenic seizures during intracranial EEG monitoring. / Khoury, Julie A.; Noe, Katherine H.; Drazkowski, Joseph F.; Sirven, Joseph I.; Zimmerman, Richard S.

In: Epilepsia, Vol. 52, No. 10, 10.2011.

Research output: Contribution to journalArticle

Khoury, JA, Noe, KH, Drazkowski, JF, Sirven, JI & Zimmerman, RS 2011, 'Iatrogenic seizures during intracranial EEG monitoring', Epilepsia, vol. 52, no. 10. https://doi.org/10.1111/j.1528-1167.2011.03161.x
Khoury JA, Noe KH, Drazkowski JF, Sirven JI, Zimmerman RS. Iatrogenic seizures during intracranial EEG monitoring. Epilepsia. 2011 Oct;52(10). https://doi.org/10.1111/j.1528-1167.2011.03161.x
Khoury, Julie A. ; Noe, Katherine H. ; Drazkowski, Joseph F. ; Sirven, Joseph I. ; Zimmerman, Richard S. / Iatrogenic seizures during intracranial EEG monitoring. In: Epilepsia. 2011 ; Vol. 52, No. 10.
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