HTLV-1 Associated Myelopathy in Canada

Christopher Power, Brian G. Weinshenker, Gregory A. Dekaban, G. C. Ebers, Gordon S. Francis, George P.a. Rice

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

We report the clinical and laboratory findings of six Canadian patients with progressive myelopathy associated with HTLV-1 infection. The diagnosis was suspected on clinical grounds and supported by serological studies and positive gene amplification. Only five had emigrated from an area endemic for HTLV-1 infection. Tropical spastic paraparesis should be considered in all patients with myelopathy, even those without standard serological markers of HTLV-1 infection. The pathogenesis of this condition and the serological and molecular biological means by which this diagnosis can be made are reviewed.

Original languageEnglish (US)
Pages (from-to)330-335
Number of pages6
JournalCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
Volume16
Issue number3
DOIs
StatePublished - Aug 1989

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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