HLA-DR antigen frequencies in a North Indian type I diabetic population

E. Bhatia, N. K. Mehra, Veena D Taneja, M. C. Vaidya, M. M. Ahuja

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Eighty-eight North Indian patients with type I, insulin-dependent diabetes mellitus (IDDM) and 113 unaffected individuals were typed for HLA-DR antigens from DR1 to DR7. The frequency of HLA-DR3 was significantly increased in the patients as compared with the controls (78.4% versus 25.7%, corrected P = 1.68 x 10-12), the relative risk (RR) of 10.52 being much higher than that reported in the Western IDDM population. HLA-DR2 showed a significant negative association (RR = 0.18, corrected P = 1.03 x 10-5), but DR4 had no relationship with IDDM in the present study (RR = 1.12, P = 0.12). These results emphasize the differences in HLA-IDDM associations among different ethnic groups.

Original languageEnglish (US)
Pages (from-to)565-567
Number of pages3
JournalDiabetes
Volume34
Issue number6
StatePublished - 1985
Externally publishedYes

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HLA-DR Antigens
Type 1 Diabetes Mellitus
Population
HLA-DR2 Antigen
HLA-DR3 Antigen
Ethnic Groups

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

Cite this

Bhatia, E., Mehra, N. K., Taneja, V. D., Vaidya, M. C., & Ahuja, M. M. (1985). HLA-DR antigen frequencies in a North Indian type I diabetic population. Diabetes, 34(6), 565-567.

HLA-DR antigen frequencies in a North Indian type I diabetic population. / Bhatia, E.; Mehra, N. K.; Taneja, Veena D; Vaidya, M. C.; Ahuja, M. M.

In: Diabetes, Vol. 34, No. 6, 1985, p. 565-567.

Research output: Contribution to journalArticle

Bhatia, E, Mehra, NK, Taneja, VD, Vaidya, MC & Ahuja, MM 1985, 'HLA-DR antigen frequencies in a North Indian type I diabetic population', Diabetes, vol. 34, no. 6, pp. 565-567.
Bhatia E, Mehra NK, Taneja VD, Vaidya MC, Ahuja MM. HLA-DR antigen frequencies in a North Indian type I diabetic population. Diabetes. 1985;34(6):565-567.
Bhatia, E. ; Mehra, N. K. ; Taneja, Veena D ; Vaidya, M. C. ; Ahuja, M. M. / HLA-DR antigen frequencies in a North Indian type I diabetic population. In: Diabetes. 1985 ; Vol. 34, No. 6. pp. 565-567.
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