Guidelines of care for the management of basal cell carcinoma

Christian Baum, Jeremy S. Bordeaux, Marc Brown, Klaus J. Busam, Daniel B. Eisen, Vivek Iyengar, Clifford Lober, David J. Margolis, Jane Messina, Alexander Miller, Stanley Miller, Eliot Mostow, Christen Mowad, Kishwer Nehal, Kristi Schmitt-Burr, Aleksandar D Sekulic, Paul Storrs, Joyce Teng, Siegrid Yu, Conway HuangKevin Boyer, Wendy Smith Begolka, Murad Alam, John Y.S. Kim, Jeffrey H. Kozlow, Bharat Mittal, Jeffrey Moyer, Thomas Olencki, Phillip Rodgers

Research output: Contribution to journalArticle

66 Scopus citations


Basal cell carcinoma (BCC) is the most common form of human cancer, with a continually increasing annual incidence in the United States. When diagnosed early, the majority of BCCs are readily treated with office-based therapy, which is highly curative. In these evidence-based guidelines of care, we provide recommendations for the management of patients with BCC, as well as an in-depth review of the best available literature in support of these recommendations. We discuss biopsy techniques for a clinically suspicious lesion and offer recommendations for the histopathologic interpretation of BCC. In the absence of a formal staging system, the best available stratification based on risk for recurrence is reviewed. With regard to treatment, we provide recommendations on treatment modalities along a broad therapeutic spectrum, ranging from topical agents and superficially destructive modalities to surgical techniques and systemic therapy. Finally, we review the available literature and provide recommendations on prevention and the most appropriate follow-up for patients in whom BCC has been diagnosed.

Original languageEnglish (US)
JournalJournal of the American Academy of Dermatology
StateAccepted/In press - Jan 1 2018


  • Basal cell carcinoma
  • Biopsy
  • Curettage
  • Metastasis
  • Phototherapy
  • Radiotherapy
  • Staging
  • Surgery
  • Surveillance
  • Topical therapy

ASJC Scopus subject areas

  • Dermatology

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  • Cite this

    Baum, C., Bordeaux, J. S., Brown, M., Busam, K. J., Eisen, D. B., Iyengar, V., Lober, C., Margolis, D. J., Messina, J., Miller, A., Miller, S., Mostow, E., Mowad, C., Nehal, K., Schmitt-Burr, K., Sekulic, A. D., Storrs, P., Teng, J., Yu, S., ... Rodgers, P. (Accepted/In press). Guidelines of care for the management of basal cell carcinoma. Journal of the American Academy of Dermatology.