Germ-free mice model for studying host–microbial interactions

Yogesh Bhattarai; Purna C. Kashyap

doi:10.1007/978-1-4939-3661-8_8

Germ-free mice model for studying host–microbial interactions

Yogesh Bhattarai, Purna C. Kashyap

Gastroenterology and Hepatology

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Germ-free (GF) mice are a relevant model system to study host–microbial interactions in health and disease. In this chapter, we underscore the importance of using GF mice model to study host–microbial interactions in obesity, immune development and gastrointestinal physiology by reviewing current literature. Furthermore, we also provide a brief protocol on how to setup a gnotobiotic facility in order to properly maintain and assess GF status in mice colonies.

Original language	English (US)
Pages (from-to)	123-135
Number of pages	13
Journal	Methods in Molecular Biology
Volume	1438
DOIs	https://doi.org/10.1007/978-1-4939-3661-8_8
State	Published - May 1 2016

Keywords

Germ-free
Gnotobiotic
Gut microbiome

ASJC Scopus subject areas

Molecular Biology
Genetics

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10.1007/978-1-4939-3661-8_8

Cite this

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Germ-free mice model for studying host–microbial interactions

Abstract

Keywords

ASJC Scopus subject areas

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