Genetics of ischaemic stroke

Pankaj Sharma; Sunaina Yadav; James F. Meschia

doi:10.1136/jnnp-2012-304834

Genetics of ischaemic stroke

Pankaj Sharma, Sunaina Yadav, James F. Meschia

Neurology

Research output: Contribution to journal › Review article › peer-review

22 Scopus citations

Abstract

Recent advances in genomics and statistical computation have allowed us to begin addressing the genetic basis of stroke at a molecular level. These advances are at the cusp of making important changes to clinical practice of some monogenic forms of stroke and, in the future, are likely to revolutionise the care provided to these patients. In this review we summarise the state of knowledge in ischaemic stroke genetics particularly in the context of how a practicing clinician can best use this knowledge.

Original language	English (US)
Pages (from-to)	1302-1308
Number of pages	7
Journal	Journal of Neurology, Neurosurgery and Psychiatry
Volume	84
Issue number	12
DOIs	https://doi.org/10.1136/jnnp-2012-304834
State	Published - Dec 2013

ASJC Scopus subject areas

Surgery
Clinical Neurology
Psychiatry and Mental health

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10.1136/jnnp-2012-304834

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title = "Genetics of ischaemic stroke",

abstract = "Recent advances in genomics and statistical computation have allowed us to begin addressing the genetic basis of stroke at a molecular level. These advances are at the cusp of making important changes to clinical practice of some monogenic forms of stroke and, in the future, are likely to revolutionise the care provided to these patients. In this review we summarise the state of knowledge in ischaemic stroke genetics particularly in the context of how a practicing clinician can best use this knowledge.",

author = "Pankaj Sharma and Sunaina Yadav and Meschia, {James F.}",

note = "Funding Information: I thank Michael O'Sullivan for critically reading the manuscript and for helpful comments. I am supported by the Deutsche Forschungsgemeinschaft (SFB 596/TPA4). No funding body had a role in the preparation of the review or in the decision to submit it for publication. ",

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AU - Yadav, Sunaina

AU - Meschia, James F.

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PY - 2013/12

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N2 - Recent advances in genomics and statistical computation have allowed us to begin addressing the genetic basis of stroke at a molecular level. These advances are at the cusp of making important changes to clinical practice of some monogenic forms of stroke and, in the future, are likely to revolutionise the care provided to these patients. In this review we summarise the state of knowledge in ischaemic stroke genetics particularly in the context of how a practicing clinician can best use this knowledge.

AB - Recent advances in genomics and statistical computation have allowed us to begin addressing the genetic basis of stroke at a molecular level. These advances are at the cusp of making important changes to clinical practice of some monogenic forms of stroke and, in the future, are likely to revolutionise the care provided to these patients. In this review we summarise the state of knowledge in ischaemic stroke genetics particularly in the context of how a practicing clinician can best use this knowledge.

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Genetics of ischaemic stroke

Abstract

ASJC Scopus subject areas

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