Genetics of coronary artery disease: Focus on genome-wide association studies

Linnea M. Baudhuin

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

With the advent of the genome-wide association (GWA) study, a promising new avenue for identifying genetic markers for complex diseases like coronary artery disease (CAD) has been opened. This avenue, however, is not without challenges and limitations, including the need for carefully designed and executed studies and the risk of false positive associations. Nonetheless, new markers have been identified through such studies that could potentially revolutionize the ways that individuals with CAD are identified and managed.

Original languageEnglish (US)
Pages (from-to)221-234
Number of pages14
JournalAmerican Journal of Translational Research
Volume1
Issue number3
StatePublished - Sep 18 2009

Keywords

  • Atherosclerosis
  • Coronary artery disease
  • Genetics
  • Genome wide association
  • Genomics
  • Myocardial infarction

ASJC Scopus subject areas

  • Molecular Medicine
  • Clinical Biochemistry
  • Cancer Research

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