GENEHUNTER: Application to analysis of bipolar pedigrees and some extensions

Hongzhe Li; Daniel J. Schaid

doi:10.1002/(SICI)1098-2272(1997)14:6<659::AID-GEPI18>3.0.CO;2-P

GENEHUNTER: Application to analysis of bipolar pedigrees and some extensions

Hongzhe Li, Daniel J. Schaid

Quantitative Health Sciences

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

A newly developed nonparametric multipoint linkage analysis (NPL) by Kruglyak et al. [1996] was applied to the data set from the Johns Hopkins Bipolar Study available through the GAW10 workshop. Our results from GENEHUNTER do not support the analyses of Stine et al. [1995]. Some possible extensions to incorporate unaffecteds are also discussed.

Original language	English (US)
Pages (from-to)	659-663
Number of pages	5
Journal	Genetic epidemiology
Volume	14
Issue number	6
DOIs	https://doi.org/10.1002/(SICI)1098-2272(1997)14:6<659::AID-GEPI18>3.0.CO;2-P
State	Published - 1997

Keywords

Bipolar disease
Multipoint linkage analysis

ASJC Scopus subject areas

Epidemiology
Genetics(clinical)

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10.1002/(SICI)1098-2272(1997)14:6<659::AID-GEPI18>3.0.CO;2-P

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abstract = "A newly developed nonparametric multipoint linkage analysis (NPL) by Kruglyak et al. [1996] was applied to the data set from the Johns Hopkins Bipolar Study available through the GAW10 workshop. Our results from GENEHUNTER do not support the analyses of Stine et al. [1995]. Some possible extensions to incorporate unaffecteds are also discussed.",

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AU - Schaid, Daniel J.

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AB - A newly developed nonparametric multipoint linkage analysis (NPL) by Kruglyak et al. [1996] was applied to the data set from the Johns Hopkins Bipolar Study available through the GAW10 workshop. Our results from GENEHUNTER do not support the analyses of Stine et al. [1995]. Some possible extensions to incorporate unaffecteds are also discussed.

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KW - Multipoint linkage analysis

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GENEHUNTER: Application to analysis of bipolar pedigrees and some extensions

Abstract

Keywords

ASJC Scopus subject areas

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