Abstract
A 57-year-old woman had a neuropsychologically documented 5-year history of a slowly progressive amnesic syndrome followed by a 1-year history of rapidly progressive dementia. There was no family history of dementia. Magnetic resonance imaging failed to show a structural basis, electroencephalography failed to show changes of Creutzfeldt-Jakob disease, and cerebrospinal fluid examination was normal. A diagnosis of Alzheimer disease was confirmed by brain biopsy. The abrupt change in disease course was unique but suggested probable overlap between posited subtypes of Alzheimer disease.
Original language | English (US) |
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Pages (from-to) | 251-253 |
Number of pages | 3 |
Journal | Alzheimer disease and associated disorders |
Volume | 12 |
Issue number | 3 |
State | Published - 1998 |
Keywords
- Alzheimer disease-
- Amnesic syndrome-
- Rapidly progressive dementia
ASJC Scopus subject areas
- Clinical Psychology
- Gerontology
- Geriatrics and Gerontology
- Psychiatry and Mental health