Frequency of familial dilated cardiomyopathy

J. B. Goerss, V. V. Michels, J. Burnett, D. J. Driscoll, F. Miller, R. Rodeheffer, A. J. Tajik, D. Schaid

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Based on evaluation of 59 probands and their families, we previously demonstrated that over 20% of patients with idiopathic dilated cardiomyopathy (DCM) have familial disease. We acquired 36 additional probands and found familial disease in 24.2% of the 95 probands in this expanded consecutively ascertained cohort. The family history, as reported by the patient and relatives, is often an unreliable indicator of familial disease because patients may be unaware of the significance of a family history of sudden death, arrhythmia or stroke. We demonstrate that careful family history with review of medical records identifies more familial cases than merely asking the patient if there is a family history of DCM. However, even such a careful family history does not identify all familial cases. Some familial cases are identified only by echocardiographic investigation of asymptomatic relatives. We found no clinical attributes of probands, other than family history, which predicted familial disease.

Original languageEnglish (US)
Pages (from-to)2-4
Number of pages3
JournalEuropean heart journal
Volume16
Issue numberSUPPL. O
StatePublished - Dec 1 1995

    Fingerprint

Keywords

  • Dilated cardiomyopathy
  • Familial

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Goerss, J. B., Michels, V. V., Burnett, J., Driscoll, D. J., Miller, F., Rodeheffer, R., Tajik, A. J., & Schaid, D. (1995). Frequency of familial dilated cardiomyopathy. European heart journal, 16(SUPPL. O), 2-4.