TY - JOUR
T1 - Fertility (male and female) and menopause
AU - Ruddy, Kathryn J.
AU - Partridge, Ann H.
PY - 2012/10/20
Y1 - 2012/10/20
N2 - The impact of oncologic treatments on fertility and menopausal symptoms is often significant for patients with cancer. Surgery, radiation, and chemotherapy can all damage the reproductive organs or the hypothalamic pituitary axis that controls them, impairing fertility and causing hormonally mediated symptoms such as hot flashes. Understanding these risks and strategies to mitigate them may substantially improve cancer survivorship care. For both female and male patients who desire a future biologic child, there are a variety of fertility preservation techniques that should be considered. For cancer survivors who experience menopausal symptoms, lifestyle changes may be beneficial, and hormonal and nonhormonal pharmacologic agents are well proven to reduce symptom burden.
AB - The impact of oncologic treatments on fertility and menopausal symptoms is often significant for patients with cancer. Surgery, radiation, and chemotherapy can all damage the reproductive organs or the hypothalamic pituitary axis that controls them, impairing fertility and causing hormonally mediated symptoms such as hot flashes. Understanding these risks and strategies to mitigate them may substantially improve cancer survivorship care. For both female and male patients who desire a future biologic child, there are a variety of fertility preservation techniques that should be considered. For cancer survivors who experience menopausal symptoms, lifestyle changes may be beneficial, and hormonal and nonhormonal pharmacologic agents are well proven to reduce symptom burden.
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U2 - 10.1200/JCO.2012.42.1966
DO - 10.1200/JCO.2012.42.1966
M3 - Review article
C2 - 23008319
AN - SCOPUS:84869145310
SN - 0732-183X
VL - 30
SP - 3705
EP - 3711
JO - Journal of Clinical Oncology
JF - Journal of Clinical Oncology
IS - 30
ER -