Factors associated with fetal shunt dislodgement in lower urinary tract obstruction

Michael P. Kurtz, Chester J. Koh, Grace Anne Jamail, Haleh Sangi-Haghpeykar, Alireza A. Shamshirsaz, Jimmy Espinoza, Darrell L. Cass, Oluyinka O. Olutoye, Olutoyin A. Olutoye, Michael C. Braun, David R. Roth, Michael A. Belfort, Rodrigo Ruano

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Objective: To identify factors associated with fetal shunt dislodgement in lower urinary tract obstruction (LUTO). Methods: We conducted a retrospective study of 42 consecutive fetuses with a diagnosis of LUTO in a tertiary fetal center between April 2013 and November 2015. Possible factors associated with prenatal shunt dislodgment were evaluated in fetuses who underwent shunt placement, including gestational age at diagnosis, gestational age at procedure, presence of ‘keyhole sign’, initial fetal bladder volume and wall thickness, prenatal ultrasonographic renal characteristics, amniotic fluid volume, presence of ascites prior to shunting, and type of fetal shunt. Results: Nineteen (46.3%) fetuses underwent shunt placement at a median gestational age of 19 (range: 16.3–31.1) weeks. Shunt dislodgement occurred in 10 (52.6%) patients. A total of 35 procedures were performed; among which 16 (45.7%) were repeat procedures. The only prenatal factor associated with shunt dislodgement was the type of the shunt; Kaplan–Meier analysis indicated that the Rocket was associated with increased likelihood of remaining orthotopic (p = 0.04). Conclusion: Fetal shunt dislodgement occurs in approximately half of the patients and appears to be associated with the type of the shunt. Future research is necessary to develop better shunt systems and to investigate different fetal therapeutic approaches.

Original languageEnglish (US)
Pages (from-to)720-725
Number of pages6
JournalPrenatal Diagnosis
Volume36
Issue number8
DOIs
StatePublished - Aug 1 2016
Externally publishedYes

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Urinary Tract
Gestational Age
Fetus
Amniotic Fluid
Ascites
Urinary Bladder
Retrospective Studies
Kidney
Therapeutics

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Genetics(clinical)

Cite this

Kurtz, M. P., Koh, C. J., Jamail, G. A., Sangi-Haghpeykar, H., Shamshirsaz, A. A., Espinoza, J., ... Ruano, R. (2016). Factors associated with fetal shunt dislodgement in lower urinary tract obstruction. Prenatal Diagnosis, 36(8), 720-725. https://doi.org/10.1002/pd.4850

Factors associated with fetal shunt dislodgement in lower urinary tract obstruction. / Kurtz, Michael P.; Koh, Chester J.; Jamail, Grace Anne; Sangi-Haghpeykar, Haleh; Shamshirsaz, Alireza A.; Espinoza, Jimmy; Cass, Darrell L.; Olutoye, Oluyinka O.; Olutoye, Olutoyin A.; Braun, Michael C.; Roth, David R.; Belfort, Michael A.; Ruano, Rodrigo.

In: Prenatal Diagnosis, Vol. 36, No. 8, 01.08.2016, p. 720-725.

Research output: Contribution to journalArticle

Kurtz, MP, Koh, CJ, Jamail, GA, Sangi-Haghpeykar, H, Shamshirsaz, AA, Espinoza, J, Cass, DL, Olutoye, OO, Olutoye, OA, Braun, MC, Roth, DR, Belfort, MA & Ruano, R 2016, 'Factors associated with fetal shunt dislodgement in lower urinary tract obstruction', Prenatal Diagnosis, vol. 36, no. 8, pp. 720-725. https://doi.org/10.1002/pd.4850
Kurtz MP, Koh CJ, Jamail GA, Sangi-Haghpeykar H, Shamshirsaz AA, Espinoza J et al. Factors associated with fetal shunt dislodgement in lower urinary tract obstruction. Prenatal Diagnosis. 2016 Aug 1;36(8):720-725. https://doi.org/10.1002/pd.4850
Kurtz, Michael P. ; Koh, Chester J. ; Jamail, Grace Anne ; Sangi-Haghpeykar, Haleh ; Shamshirsaz, Alireza A. ; Espinoza, Jimmy ; Cass, Darrell L. ; Olutoye, Oluyinka O. ; Olutoye, Olutoyin A. ; Braun, Michael C. ; Roth, David R. ; Belfort, Michael A. ; Ruano, Rodrigo. / Factors associated with fetal shunt dislodgement in lower urinary tract obstruction. In: Prenatal Diagnosis. 2016 ; Vol. 36, No. 8. pp. 720-725.
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