TY - JOUR
T1 - Facial nerve schwannomas of the cerebellopontine angle
T2 - The Mayo Clinic experience
AU - Jacob, Jeffrey T.
AU - Driscoll, Colin L.W.
AU - Link, Michael J.
PY - 2012/8
Y1 - 2012/8
N2 - Background: There is often controversy regarding the optimal management for patients with facial nerve schwannomas (FNSs) of the cerebellopontine angle (CPA). Methods: The clinical and radiological outcomes in 14 patients with CPA FNS were retrospectively reviewed. Results: Patients underwent resection with anatomic nerve preservation ( n = 3), facial-hypoglossal nerve anastomosis ( n = 4), gamma knife radiosurgery (GKS) (n = 6), or observation ( n = 1). A total of 83% of tumors that underwent GKS were stable or decreased in size. No patient who underwent resection showed evidence of tumor recurrence; the tumor under observation remained unchanged with normal facial function at the time of the last follow-up. Facial function was decreased in 57%, stable in 14%, and improved in 29% of those who underwent microsurgery. A total of 67% of patients who underwent GKS had stable facial function. Serviceable hearing was maintained in 50% of patients in the GKS group and 67% of the tumor resection group. Mean and median follow-up was 48 and 43 months, respectively (range, 12 to 95 months). Conclusion: Observation should be the primary management when encountered with FNS of the CPA in those with good neurologic function. Microsurgery or radiosurgery may be used in those with poor facial function or tumor progression.
AB - Background: There is often controversy regarding the optimal management for patients with facial nerve schwannomas (FNSs) of the cerebellopontine angle (CPA). Methods: The clinical and radiological outcomes in 14 patients with CPA FNS were retrospectively reviewed. Results: Patients underwent resection with anatomic nerve preservation ( n = 3), facial-hypoglossal nerve anastomosis ( n = 4), gamma knife radiosurgery (GKS) (n = 6), or observation ( n = 1). A total of 83% of tumors that underwent GKS were stable or decreased in size. No patient who underwent resection showed evidence of tumor recurrence; the tumor under observation remained unchanged with normal facial function at the time of the last follow-up. Facial function was decreased in 57%, stable in 14%, and improved in 29% of those who underwent microsurgery. A total of 67% of patients who underwent GKS had stable facial function. Serviceable hearing was maintained in 50% of patients in the GKS group and 67% of the tumor resection group. Mean and median follow-up was 48 and 43 months, respectively (range, 12 to 95 months). Conclusion: Observation should be the primary management when encountered with FNS of the CPA in those with good neurologic function. Microsurgery or radiosurgery may be used in those with poor facial function or tumor progression.
KW - Cerebellopontine angle
KW - Facial nerve
KW - Schwannoma
KW - Vestibular schwannoma
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U2 - 10.1055/s-0032-1312718
DO - 10.1055/s-0032-1312718
M3 - Article
AN - SCOPUS:84896346659
SN - 2193-634X
VL - 73
SP - 230
EP - 235
JO - Journal of Neurological Surgery, Part B: Skull Base
JF - Journal of Neurological Surgery, Part B: Skull Base
IS - 4
ER -