Extraction of the hepatic vasculature in rats using 3-D micro-CT images

Shu Yen Wan, Atilla P. Kiraly, Erik L. Ritman, William E. Higgins

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

High-resolution micro-computed tomography (CT) scanners now exist for imaging small animals. In particular, such a scanner can generate very large three-dimensional (3-D) digital images of the rat's hepatic vasculature. These images provide data on the overall structure and function of such complex vascular trees. Unfortunately, human operators have extreme difficulty in extracting the extensive vasculature contained in the images. Also, no suitable tree representation exists that permits straight-forward structural analysis and information retrieval. This work proposes an automatic procedure for extracting and representing such a vascular tree. The procedure is both computation and memory efficient and runs on current PCs. As the results demonstrate, the procedure faithfully follows human-defined measurements and provides far more information than can be defined interactively.

Original languageEnglish (US)
Pages (from-to)964-971
Number of pages8
JournalIEEE Transactions on Medical Imaging
Volume19
Issue number9
DOIs
StatePublished - Sep 2000
Externally publishedYes

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Information retrieval
Structural analysis
Tomography
Rats
Animals
Imaging techniques
Data storage equipment
Blood Vessels
Liver
X-Ray Computed Tomography Scanners
Three-Dimensional Imaging
Information Storage and Retrieval

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Electrical and Electronic Engineering
  • Computer Science Applications
  • Computational Theory and Mathematics

Cite this

Extraction of the hepatic vasculature in rats using 3-D micro-CT images. / Wan, Shu Yen; Kiraly, Atilla P.; Ritman, Erik L.; Higgins, William E.

In: IEEE Transactions on Medical Imaging, Vol. 19, No. 9, 09.2000, p. 964-971.

Research output: Contribution to journalArticle

Wan, Shu Yen ; Kiraly, Atilla P. ; Ritman, Erik L. ; Higgins, William E. / Extraction of the hepatic vasculature in rats using 3-D micro-CT images. In: IEEE Transactions on Medical Imaging. 2000 ; Vol. 19, No. 9. pp. 964-971.
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