Extensibility of the supraspinatus muscle can be predicted by combining shear wave elastography and magnetic resonance imaging-measured quantitative metrics of stiffness and volumetric fat infiltration

A cadaveric study

Hugo Giambini, Taku Hatta, Asghar Rezaei, Kai Nan An

Research output: Contribution to journalArticle

Abstract

Background: A torn rotator cuff tendon will retract over time causing changes in muscle properties and decreasing its extensibility, or deformation. During surgery, large tensile loads are applied to bring the torn tendon to the footprint. Poor muscle extensibility and large tensile stresses at the repair might lead to gap formation or re-tear of the repair. A quantitative evaluation of muscle properties could be used to predict the extensibility of the supraspinatus (SSP) muscle. Method: Magnetic resonance imaging (MRI)-measured volumetric fat fraction and shear wave elastography (SWE)-measured elastic modulus of the SSP muscle were obtained on seventeen cadaveric shoulders. Experimental extensibility and stiffness were then measured by axially pulling the tendon up-to 60 N. Univariate and multivariate analyses were used to determine the correlation and contribution of fat fraction and elastic modulus to experimental outcomes. Findings: SWE moduli negatively correlated with SSP muscle extensibility (r = 0.54–0.58, P ≤ 0.0259); fat fraction resulted in a positive correlation (r = 0.69, P = 0.0021). SWE measurements, solely, explained up to 34% and 33% of the variability in measured extensibility and stiffness, respectively. Fat Fraction, solely, explained 48% of the variability in extensibility and 36% of the variability in stiffness. These methods combined predicted up to 62% of the musculotendinous extensibility. Interpretation: This study showed a comprehensive quantitative assessment of SSP muscle properties using SWE to estimate stiffness and MRI to measure fatty infiltration. The extensibility of the detached muscle/tendon unit was highly correlated to material properties of the muscle when these methods were used in combination.

Original languageEnglish (US)
Pages (from-to)144-149
Number of pages6
JournalClinical Biomechanics
Volume57
DOIs
StatePublished - Aug 1 2018

Fingerprint

Elasticity Imaging Techniques
Rotator Cuff
Fats
Magnetic Resonance Imaging
Muscles
Tendons
Elastic Modulus
Tears
Multivariate Analysis

Keywords

  • Magnetic resonance imaging
  • Muscle properties
  • Rotator cuff tear
  • Tendon retraction
  • Ultrasound

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine

Cite this

@article{f10187fd31cc4006b6b73ff2fc14a7dc,
title = "Extensibility of the supraspinatus muscle can be predicted by combining shear wave elastography and magnetic resonance imaging-measured quantitative metrics of stiffness and volumetric fat infiltration: A cadaveric study",
abstract = "Background: A torn rotator cuff tendon will retract over time causing changes in muscle properties and decreasing its extensibility, or deformation. During surgery, large tensile loads are applied to bring the torn tendon to the footprint. Poor muscle extensibility and large tensile stresses at the repair might lead to gap formation or re-tear of the repair. A quantitative evaluation of muscle properties could be used to predict the extensibility of the supraspinatus (SSP) muscle. Method: Magnetic resonance imaging (MRI)-measured volumetric fat fraction and shear wave elastography (SWE)-measured elastic modulus of the SSP muscle were obtained on seventeen cadaveric shoulders. Experimental extensibility and stiffness were then measured by axially pulling the tendon up-to 60 N. Univariate and multivariate analyses were used to determine the correlation and contribution of fat fraction and elastic modulus to experimental outcomes. Findings: SWE moduli negatively correlated with SSP muscle extensibility (r = 0.54–0.58, P ≤ 0.0259); fat fraction resulted in a positive correlation (r = 0.69, P = 0.0021). SWE measurements, solely, explained up to 34{\%} and 33{\%} of the variability in measured extensibility and stiffness, respectively. Fat Fraction, solely, explained 48{\%} of the variability in extensibility and 36{\%} of the variability in stiffness. These methods combined predicted up to 62{\%} of the musculotendinous extensibility. Interpretation: This study showed a comprehensive quantitative assessment of SSP muscle properties using SWE to estimate stiffness and MRI to measure fatty infiltration. The extensibility of the detached muscle/tendon unit was highly correlated to material properties of the muscle when these methods were used in combination.",
keywords = "Magnetic resonance imaging, Muscle properties, Rotator cuff tear, Tendon retraction, Ultrasound",
author = "Hugo Giambini and Taku Hatta and Asghar Rezaei and An, {Kai Nan}",
year = "2018",
month = "8",
day = "1",
doi = "10.1016/j.clinbiomech.2018.07.001",
language = "English (US)",
volume = "57",
pages = "144--149",
journal = "Clinical Biomechanics",
issn = "0268-0033",
publisher = "Elsevier Limited",

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TY - JOUR

T1 - Extensibility of the supraspinatus muscle can be predicted by combining shear wave elastography and magnetic resonance imaging-measured quantitative metrics of stiffness and volumetric fat infiltration

T2 - A cadaveric study

AU - Giambini, Hugo

AU - Hatta, Taku

AU - Rezaei, Asghar

AU - An, Kai Nan

PY - 2018/8/1

Y1 - 2018/8/1

N2 - Background: A torn rotator cuff tendon will retract over time causing changes in muscle properties and decreasing its extensibility, or deformation. During surgery, large tensile loads are applied to bring the torn tendon to the footprint. Poor muscle extensibility and large tensile stresses at the repair might lead to gap formation or re-tear of the repair. A quantitative evaluation of muscle properties could be used to predict the extensibility of the supraspinatus (SSP) muscle. Method: Magnetic resonance imaging (MRI)-measured volumetric fat fraction and shear wave elastography (SWE)-measured elastic modulus of the SSP muscle were obtained on seventeen cadaveric shoulders. Experimental extensibility and stiffness were then measured by axially pulling the tendon up-to 60 N. Univariate and multivariate analyses were used to determine the correlation and contribution of fat fraction and elastic modulus to experimental outcomes. Findings: SWE moduli negatively correlated with SSP muscle extensibility (r = 0.54–0.58, P ≤ 0.0259); fat fraction resulted in a positive correlation (r = 0.69, P = 0.0021). SWE measurements, solely, explained up to 34% and 33% of the variability in measured extensibility and stiffness, respectively. Fat Fraction, solely, explained 48% of the variability in extensibility and 36% of the variability in stiffness. These methods combined predicted up to 62% of the musculotendinous extensibility. Interpretation: This study showed a comprehensive quantitative assessment of SSP muscle properties using SWE to estimate stiffness and MRI to measure fatty infiltration. The extensibility of the detached muscle/tendon unit was highly correlated to material properties of the muscle when these methods were used in combination.

AB - Background: A torn rotator cuff tendon will retract over time causing changes in muscle properties and decreasing its extensibility, or deformation. During surgery, large tensile loads are applied to bring the torn tendon to the footprint. Poor muscle extensibility and large tensile stresses at the repair might lead to gap formation or re-tear of the repair. A quantitative evaluation of muscle properties could be used to predict the extensibility of the supraspinatus (SSP) muscle. Method: Magnetic resonance imaging (MRI)-measured volumetric fat fraction and shear wave elastography (SWE)-measured elastic modulus of the SSP muscle were obtained on seventeen cadaveric shoulders. Experimental extensibility and stiffness were then measured by axially pulling the tendon up-to 60 N. Univariate and multivariate analyses were used to determine the correlation and contribution of fat fraction and elastic modulus to experimental outcomes. Findings: SWE moduli negatively correlated with SSP muscle extensibility (r = 0.54–0.58, P ≤ 0.0259); fat fraction resulted in a positive correlation (r = 0.69, P = 0.0021). SWE measurements, solely, explained up to 34% and 33% of the variability in measured extensibility and stiffness, respectively. Fat Fraction, solely, explained 48% of the variability in extensibility and 36% of the variability in stiffness. These methods combined predicted up to 62% of the musculotendinous extensibility. Interpretation: This study showed a comprehensive quantitative assessment of SSP muscle properties using SWE to estimate stiffness and MRI to measure fatty infiltration. The extensibility of the detached muscle/tendon unit was highly correlated to material properties of the muscle when these methods were used in combination.

KW - Magnetic resonance imaging

KW - Muscle properties

KW - Rotator cuff tear

KW - Tendon retraction

KW - Ultrasound

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U2 - 10.1016/j.clinbiomech.2018.07.001

DO - 10.1016/j.clinbiomech.2018.07.001

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VL - 57

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EP - 149

JO - Clinical Biomechanics

JF - Clinical Biomechanics

SN - 0268-0033

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