Exercise attenuates the major hallmarks of aging

Nuria Garatachea, Helios Pareja-Galeano, Fabian Sanchis-Gomar, Alejandro Santos-Lozano, Carmen Fiuza-Luces, María Morán, Enzo Emanuele, Michael J. Joyner, Alejandro Lucia

Research output: Contribution to journalArticle

72 Scopus citations


Regular exercise has multi-system anti-aging effects. Here we summarize how exercise impacts the major hallmarks of aging. We propose that, besides searching for novel pharmaceutical targets of the aging process, more research efforts should be devoted to gaining insights into the molecular mediators of the benefits of exercise and to implement effective exercise interventions for elderly people.

Original languageEnglish (US)
Pages (from-to)57-89
Number of pages33
JournalRejuvenation Research
Issue number1
StatePublished - Feb 1 2015


ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology

Cite this

Garatachea, N., Pareja-Galeano, H., Sanchis-Gomar, F., Santos-Lozano, A., Fiuza-Luces, C., Morán, M., Emanuele, E., Joyner, M. J., & Lucia, A. (2015). Exercise attenuates the major hallmarks of aging. Rejuvenation Research, 18(1), 57-89. https://doi.org/10.1089/rej.2014.1623