TY - JOUR
T1 - Etiopathogenesis and prognosis of cerebral ischemia in young adults.
AU - Lanzino, G.
AU - Andreoli, A.
AU - Pasquale, G. Di
AU - Urbinati, S.
AU - Limoni, P.
AU - Serracchioli, A.
AU - Lusa, A.
AU - Pinelli, G.
AU - Testa, C.
AU - Tognetti, F.
PY - 1991/10
Y1 - 1991/10
N2 - ABSTRACT Etiology and long‐term prognosis were prospectively investigated in 155 consecutive patients (96 men and 59 women), aged 16 to 45 years, referred to our Neurosurgical Unit with cerebral transient ischemic attacks or infarction during the period 1978‐1988. All patients underwent neurological and medical‐cardiological evaluation, cerebral computerized tomography scanning, electrocardiogram, and laboratory tests. Two‐dimensional echocardiography was performed in 123 cases (79%), cerebral angiography in 147 (95%). Atherosclerosis was the leading etiology occurring in 48 patients (31%). A cardioemboiic disorder was considered the probable cause of ischemia in 8 cases (5.1%). Further possible etiologies were contraceptive pill assumption (5.8% of the total, but 15.3% within the female group), spontaneous arterial dissection (4.5%), migraine (4%), puerperium (2.6%), cervical trauma (2.6%), and other, more uncommon conditions. Despite extensive evaluation, the cause of cerebral ischemia remained unknown in 40% of cases. All patients received antiplatelet medication and 16 underwent surgery. The long‐term outcome at a mean follow‐up of 5.8 years was favorable: 91% of subjects resumed their work on a full or part‐time basis. 1991 Blackwell Munksgaard
AB - ABSTRACT Etiology and long‐term prognosis were prospectively investigated in 155 consecutive patients (96 men and 59 women), aged 16 to 45 years, referred to our Neurosurgical Unit with cerebral transient ischemic attacks or infarction during the period 1978‐1988. All patients underwent neurological and medical‐cardiological evaluation, cerebral computerized tomography scanning, electrocardiogram, and laboratory tests. Two‐dimensional echocardiography was performed in 123 cases (79%), cerebral angiography in 147 (95%). Atherosclerosis was the leading etiology occurring in 48 patients (31%). A cardioemboiic disorder was considered the probable cause of ischemia in 8 cases (5.1%). Further possible etiologies were contraceptive pill assumption (5.8% of the total, but 15.3% within the female group), spontaneous arterial dissection (4.5%), migraine (4%), puerperium (2.6%), cervical trauma (2.6%), and other, more uncommon conditions. Despite extensive evaluation, the cause of cerebral ischemia remained unknown in 40% of cases. All patients received antiplatelet medication and 16 underwent surgery. The long‐term outcome at a mean follow‐up of 5.8 years was favorable: 91% of subjects resumed their work on a full or part‐time basis. 1991 Blackwell Munksgaard
KW - cardio‐embolism
KW - carotid atherosclerosis
KW - cerebral angiography
KW - cerebrovascular disease
KW - young adults
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U2 - 10.1111/j.1600-0404.1991.tb04962.x
DO - 10.1111/j.1600-0404.1991.tb04962.x
M3 - Article
C2 - 1772005
AN - SCOPUS:0026004649
SN - 0001-6314
VL - 84
SP - 321
EP - 325
JO - Acta neurologica Scandinavica
JF - Acta neurologica Scandinavica
IS - 4
ER -