Endotracheal castleman disease: A case report

Truc T. Pham, James H. Harrell, Brian Herndier, Eunhee S. Yi

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Castleman disease (CD) is an uncommon benign lymphoid hyperplasia with several clinical and morphologic variants associated with distinct outcomes. Pulmonary CD has been reported as a rare extranodal manifestation in the literature. However, CD presenting as an obstructive mass in the airway has not been documented. We report a case of localized hyaline-vascular CD presenting as an endotracheal lesion. The patient was a 50-year-old woman with Marfan syndrome. The lesion caused near-complete airway obstruction with respiratory insufficiency. The patient underwent laser resection, and the diagnosis of CD was supported by comprehensive studies including histopathologic, immunohistochemical, and molecular methods.

Original languageEnglish (US)
Pages (from-to)590-592
Number of pages3
JournalChest
Volume131
Issue number2
DOIs
StatePublished - Feb 2007

Keywords

  • Castleman disease
  • Endotracheal
  • Fluorescent in situ hybridization
  • Gene rearrangement
  • Hyaline vascular type
  • Immunohistochemistry
  • Laser
  • Polymerase chain reaction

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Endotracheal castleman disease: A case report'. Together they form a unique fingerprint.

  • Cite this

    Pham, T. T., Harrell, J. H., Herndier, B., & Yi, E. S. (2007). Endotracheal castleman disease: A case report. Chest, 131(2), 590-592. https://doi.org/10.1378/chest.06-1346