Abstract
Castleman disease (CD) is an uncommon benign lymphoid hyperplasia with several clinical and morphologic variants associated with distinct outcomes. Pulmonary CD has been reported as a rare extranodal manifestation in the literature. However, CD presenting as an obstructive mass in the airway has not been documented. We report a case of localized hyaline-vascular CD presenting as an endotracheal lesion. The patient was a 50-year-old woman with Marfan syndrome. The lesion caused near-complete airway obstruction with respiratory insufficiency. The patient underwent laser resection, and the diagnosis of CD was supported by comprehensive studies including histopathologic, immunohistochemical, and molecular methods.
Original language | English (US) |
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Pages (from-to) | 590-592 |
Number of pages | 3 |
Journal | Chest |
Volume | 131 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2007 |
Keywords
- Castleman disease
- Endotracheal
- Fluorescent in situ hybridization
- Gene rearrangement
- Hyaline vascular type
- Immunohistochemistry
- Laser
- Polymerase chain reaction
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
- Critical Care and Intensive Care Medicine
- Cardiology and Cardiovascular Medicine