Background: EUS is the most accurate preoparative technique for ataging the depth of invasion of advanced (T2-T4) esophageal cancer. EUS experience with staging EEC (T1), however, is limited The purpose of this study was to assess the accuracy and limitations of conventional EUS in staging EEC in the high-risk population of Linxian, China. Methods: Endoscopy, chromoendoscopy (using Lugol's iodine), and EUS were carried out on 40 consciously sedated patients with biopsy-proven severe squamous dysplasia or squamous EC, using an Olympus UM20 echoendoscope with switchable 7.5MHz and 12MHz ultrasound frequencies. Tha caliac nodes, pericardial nodes, and the entire esophagus were systematically examined and videotaped, and stop-frame photographs were taken every 1 cm from the EGJ to the UES. 10 of tha 40 patients underwent surgical resection 1-8 weeks after EUS. The resected specimens were cut in 2.0×0.4cm blocks and totally embedded. Results: EUS Histology m sm mp a Tis 1 1 T1sm 1 3 1 T1sm 1 1 T2 1 The T1sm lesions were deeply invasive, adjacent to the mp. Conclusions: In this preliminary study, conventional EUS, using 7.5MHz and 12MHz ultrasound frequencies, showed limited accuracy for estimating the depth of invasion of EEC. Higher frequency EUS instruments and the use of catheter echoprobes during endoscopy may be required for accurate staging of those early lesions.
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging