Endoscopic mucosal resection and endoscopic submucosal dissection in esophageal and gastric cancers

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28 Citations (Scopus)

Abstract

Purpose Of review: To summarize the literature to date on endoscopic mucosal removal techniques as applied to the upper gastrointestinal tract, predominantly the stomach and esophagus. This is an area that has rapidly advanced in terms of new procedures and techniques with a large body of outcomes that support their use. Recent findings: The resection techniques can be divided into two forms, mucosal resection and submucosal dissection. Mucosal resection is typically done with cap techniques and is more suitable for removable of neoplastic lesions that are less than 1.5 cm in size. Submucosal dissection techniques are more difficult, associated with increased complications, and typically reserved for lesions greater than 1.5 cm and less than 3 cm in size. Ideal lesions for mucosal resection are generally flat and are located in areas easily accessible by the endoscope. Summary: Endoscopic tissue removal methods are capable of removing neoplastic lesions en bloc in the upper gastrointestinal tract. These techniques fulfill cancer treatment guidelines by having histological confirmation of total removal of neoplastic lesions with assessment of the margins of resections. Long-term clinical outcomes of these techniques are emerging and seem promising in terms of disease-free and overall survival.

Original languageEnglish (US)
Pages (from-to)453-458
Number of pages6
JournalCurrent Opinion in Gastroenterology
Volume26
Issue number5
DOIs
StatePublished - Sep 2010

Fingerprint

Upper Gastrointestinal Tract
Esophageal Neoplasms
Stomach Neoplasms
Dissection
Endoscopes
Esophagus
Disease-Free Survival
Stomach
Guidelines
Neoplasms
Endoscopic Mucosal Resection
Margins of Excision

Keywords

  • Barrett's esophagus
  • endoscopic mucosal resection
  • endoscopic submucosal dissection
  • endoscopic therapy
  • esophageal neoplasm
  • gastric neoplasm

ASJC Scopus subject areas

  • Gastroenterology

Cite this

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title = "Endoscopic mucosal resection and endoscopic submucosal dissection in esophageal and gastric cancers",
abstract = "Purpose Of review: To summarize the literature to date on endoscopic mucosal removal techniques as applied to the upper gastrointestinal tract, predominantly the stomach and esophagus. This is an area that has rapidly advanced in terms of new procedures and techniques with a large body of outcomes that support their use. Recent findings: The resection techniques can be divided into two forms, mucosal resection and submucosal dissection. Mucosal resection is typically done with cap techniques and is more suitable for removable of neoplastic lesions that are less than 1.5 cm in size. Submucosal dissection techniques are more difficult, associated with increased complications, and typically reserved for lesions greater than 1.5 cm and less than 3 cm in size. Ideal lesions for mucosal resection are generally flat and are located in areas easily accessible by the endoscope. Summary: Endoscopic tissue removal methods are capable of removing neoplastic lesions en bloc in the upper gastrointestinal tract. These techniques fulfill cancer treatment guidelines by having histological confirmation of total removal of neoplastic lesions with assessment of the margins of resections. Long-term clinical outcomes of these techniques are emerging and seem promising in terms of disease-free and overall survival.",
keywords = "Barrett's esophagus, endoscopic mucosal resection, endoscopic submucosal dissection, endoscopic therapy, esophageal neoplasm, gastric neoplasm",
author = "Wang, {Kenneth Ke Ning} and Iyer, {Prasad G} and Jianmin Tian",
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KW - Barrett's esophagus

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KW - endoscopic submucosal dissection

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KW - gastric neoplasm

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