Endomyocardial biopsy-integrating electrode at the bioptome tip

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: The addition of electroanatomic mapping to a standard echo-guided endomyocardial biopsy could identify areas of abnormal pathology and increase the diagnostic yield of the procedure. Methods and results: In this demonstration of a novel technique, a 45-year-old woman with clinical suspicion for cardiac sarcoidosis underwent right ventricular bipolar electroanatomical mapping with identification of areas of signal fractionation and low voltage. A bioptome, configured to record an electrogram from the tip, was then visualized on the three-dimensional electroanatomic mapping (3DEAM) system, and directed to these areas. The biopsy was assisted by the use of a steerable introducer sheath, and by recording unipolar and extended bipolar signals from the bioptome tip. A prominent change in the signal was detected by the electrode at the bioptome tip when the jaws closed on the endomyocardial tissue. Patient tolerated the procedure without complications, and the biopsied samples were appropriate for pathological analysis. Conclusions: Using existing technology, the 3DEAM, which integrates unipolar and bipolar signal from the bioptome tip, is feasible, and can be safely added to a standard echocardiographically guided endomyocardial biopsy. Future studies should investigate whether such a technique could increase the safety and diagnostic yield of endomyocardial biopsies in patients with suspected cardiomyopathies.

Original languageEnglish (US)
Pages (from-to)66-69
Number of pages4
JournalTherapeutic Advances in Cardiovascular Disease
Volume9
Issue number3
DOIs
StatePublished - Jun 3 2015

Fingerprint

Electrodes
Biopsy
Sarcoidosis
Jaw
Cardiomyopathies
Pathology
Technology
Safety

Keywords

  • electroanatomic mapping
  • endomyocardial biopsy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)

Cite this

Endomyocardial biopsy-integrating electrode at the bioptome tip. / Konecny, Tomas; Noseworthy, Peter; Kapa, Suraj; Cooper, Leslie T Jr.; Mulpuru, Siva; Sandhu, Gurpreet S.; Asirvatham, Samuel J.

In: Therapeutic Advances in Cardiovascular Disease, Vol. 9, No. 3, 03.06.2015, p. 66-69.

Research output: Contribution to journalArticle

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AU - Sandhu, Gurpreet S.

AU - Asirvatham, Samuel J

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