Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation

Mario M. Alvarez, Joanna Aizenberg, Mostafa Analoui, Anne M. Andrews, Gili Bisker, Edward S. Boyden, Roger D. Kamm, Jeffrey M. Karp, David J. Mooney, Rahmi Oklu, Dan Peer, Michelle Stolzoff, Michael S. Strano, Grissel Trujillo-De Santiago, Thomas J. Webster, Paul S. Weiss, Ali Khademhosseini

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

We discuss the state of the art and innovative micro- and nanoscale technologies that are finding niches and opening up new opportunities in medicine, particularly in diagnostic and therapeutic applications. We take the design of point-of-care applications and the capture of circulating tumor cells as illustrative examples of the integration of micro- and nanotechnologies into solutions of diagnostic challenges. We describe several novel nanotechnologies that enable imaging cellular structures and molecular events. In therapeutics, we describe the utilization of micro- and nanotechnologies in applications including drug delivery, tissue engineering, and pharmaceutical development/testing. In addition, we discuss relevant challenges that micro- and nanotechnologies face in achieving cost-effective and widespread clinical implementation as well as forecasted applications of micro- and nanotechnologies in medicine.

Original languageEnglish (US)
Pages (from-to)5195-5214
Number of pages20
JournalACS Nano
Volume11
Issue number6
DOIs
StatePublished - Jun 27 2017

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nanotechnology
medicine
Nanotechnology
microbalances
Medicine
emerging
trends
tissue engineering
Drug delivery
Tissue engineering
Drug products
Tumors
delivery
drugs
tumors
Cells
costs
Imaging techniques
Testing
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Materials Science(all)
  • Engineering(all)
  • Physics and Astronomy(all)

Cite this

Alvarez, M. M., Aizenberg, J., Analoui, M., Andrews, A. M., Bisker, G., Boyden, E. S., ... Khademhosseini, A. (2017). Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation. ACS Nano, 11(6), 5195-5214. https://doi.org/10.1021/acsnano.7b01493

Emerging Trends in Micro- and Nanoscale Technologies in Medicine : From Basic Discoveries to Translation. / Alvarez, Mario M.; Aizenberg, Joanna; Analoui, Mostafa; Andrews, Anne M.; Bisker, Gili; Boyden, Edward S.; Kamm, Roger D.; Karp, Jeffrey M.; Mooney, David J.; Oklu, Rahmi; Peer, Dan; Stolzoff, Michelle; Strano, Michael S.; Trujillo-De Santiago, Grissel; Webster, Thomas J.; Weiss, Paul S.; Khademhosseini, Ali.

In: ACS Nano, Vol. 11, No. 6, 27.06.2017, p. 5195-5214.

Research output: Contribution to journalArticle

Alvarez, MM, Aizenberg, J, Analoui, M, Andrews, AM, Bisker, G, Boyden, ES, Kamm, RD, Karp, JM, Mooney, DJ, Oklu, R, Peer, D, Stolzoff, M, Strano, MS, Trujillo-De Santiago, G, Webster, TJ, Weiss, PS & Khademhosseini, A 2017, 'Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation', ACS Nano, vol. 11, no. 6, pp. 5195-5214. https://doi.org/10.1021/acsnano.7b01493
Alvarez MM, Aizenberg J, Analoui M, Andrews AM, Bisker G, Boyden ES et al. Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation. ACS Nano. 2017 Jun 27;11(6):5195-5214. https://doi.org/10.1021/acsnano.7b01493
Alvarez, Mario M. ; Aizenberg, Joanna ; Analoui, Mostafa ; Andrews, Anne M. ; Bisker, Gili ; Boyden, Edward S. ; Kamm, Roger D. ; Karp, Jeffrey M. ; Mooney, David J. ; Oklu, Rahmi ; Peer, Dan ; Stolzoff, Michelle ; Strano, Michael S. ; Trujillo-De Santiago, Grissel ; Webster, Thomas J. ; Weiss, Paul S. ; Khademhosseini, Ali. / Emerging Trends in Micro- and Nanoscale Technologies in Medicine : From Basic Discoveries to Translation. In: ACS Nano. 2017 ; Vol. 11, No. 6. pp. 5195-5214.
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