We assessed the efficacy of CD4/CD8 ratio of the peripheral lymphocytes as a prognostic factor in 25 severely handicapped subjects with mental retardation, who were admitted to Suzuka Byoin National Sanatorium. The patients were divided into two groups; Group A (CD4/CD8<1, 12 patients) and Croup B (CD4/CD8>1, 13 patients). Three-year follow-up study revealed that six patients beloging to the Group A died but all patients belonging to the Group B survived. These data suggest that the CD4/CD8 ratio of peripheral lymphocytes might be one of the beneficial prognostic factors in severely handicapped subjects with mental retardation.
- CD4/CD8 ratio
- prognostic factor
- severely handicapped subjects
- surface marker of peripheral lymphocytes
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