Efficacy of CD4/CD8 ratio of peripheral lymphocytes as a prognostic factor in severely handicapped people with mental retardation

Masamune Higashigawa; Toshiya Kamiya; Chizuko Nakano; Masako Kubo; Hajime Kawasaki; Kazuo Higuchi; Hirohito Kita; Toshiaki Ihara; Hitoshi Kamiya; Minoru Sakurai

doi:10.11261/iryo1946.45.651

Efficacy of CD4/CD8 ratio of peripheral lymphocytes as a prognostic factor in severely handicapped people with mental retardation

Masamune Higashigawa, Toshiya Kamiya, Chizuko Nakano, Masako Kubo, Hajime Kawasaki, Kazuo Higuchi, Hirohito Kita, Toshiaki Ihara, Hitoshi Kamiya, Minoru Sakurai

Allergy, Asthma and Clinical Immunology

Research output: Contribution to journal › Article › peer-review

Abstract

We assessed the efficacy of CD4/CD8 ratio of the peripheral lymphocytes as a prognostic factor in 25 severely handicapped subjects with mental retardation, who were admitted to Suzuka Byoin National Sanatorium. The patients were divided into two groups; Group A (CD4/CD8<1, 12 patients) and Croup B (CD4/CD8>1, 13 patients). Three-year follow-up study revealed that six patients beloging to the Group A died but all patients belonging to the Group B survived. These data suggest that the CD4/CD8 ratio of peripheral lymphocytes might be one of the beneficial prognostic factors in severely handicapped subjects with mental retardation.

Original language	English (US)
Pages (from-to)	651-655
Number of pages	5
Journal	Japanese Journal of National Medical Services
Volume	45
Issue number	7
DOIs	https://doi.org/10.11261/iryo1946.45.651
State	Published - Jul 1991

Keywords

CD4/CD8 ratio
prognostic factor
severely handicapped subjects
surface marker of peripheral lymphocytes

ASJC Scopus subject areas

General Medicine

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10.11261/iryo1946.45.651

Cite this

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abstract = "We assessed the efficacy of CD4/CD8 ratio of the peripheral lymphocytes as a prognostic factor in 25 severely handicapped subjects with mental retardation, who were admitted to Suzuka Byoin National Sanatorium. The patients were divided into two groups; Group A (CD4/CD8<1, 12 patients) and Croup B (CD4/CD8>1, 13 patients). Three-year follow-up study revealed that six patients beloging to the Group A died but all patients belonging to the Group B survived. These data suggest that the CD4/CD8 ratio of peripheral lymphocytes might be one of the beneficial prognostic factors in severely handicapped subjects with mental retardation.",

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AU - Higashigawa, Masamune

AU - Kamiya, Toshiya

AU - Nakano, Chizuko

AU - Kubo, Masako

AU - Kawasaki, Hajime

AU - Higuchi, Kazuo

AU - Kita, Hirohito

AU - Ihara, Toshiaki

AU - Kamiya, Hitoshi

AU - Sakurai, Minoru

PY - 1991/7

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KW - surface marker of peripheral lymphocytes

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Efficacy of CD4/CD8 ratio of peripheral lymphocytes as a prognostic factor in severely handicapped people with mental retardation

Abstract

Keywords

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