Efficacy of CD4/CD8 ratio of peripheral lymphocytes as a prognostic factor in severely handicapped people with mental retardation

Masamune Higashigawa, Toshiya Kamiya, Chizuko Nakano, Masako Kubo, Hajime Kawasaki, Kazuo Higuchi, Hirohito Kita, Toshiaki Ihara, Hitoshi Kamiya, Minoru Sakurai

Research output: Contribution to journalArticle

Abstract

We assessed the efficacy of CD4/CD8 ratio of the peripheral lymphocytes as a prognostic factor in 25 severely handicapped subjects with mental retardation, who were admitted to Suzuka Byoin National Sanatorium. The patients were divided into two groups; Group A (CD4/CD8<1, 12 patients) and Croup B (CD4/CD8>1, 13 patients). Three-year follow-up study revealed that six patients beloging to the Group A died but all patients belonging to the Group B survived. These data suggest that the CD4/CD8 ratio of peripheral lymphocytes might be one of the beneficial prognostic factors in severely handicapped subjects with mental retardation.

Original languageEnglish (US)
Pages (from-to)651-655
Number of pages5
JournalJapanese Journal of National Medical Services
Volume45
Issue number7
DOIs
StatePublished - 1991
Externally publishedYes

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Keywords

  • CD4/CD8 ratio
  • prognostic factor
  • severely handicapped subjects
  • surface marker of peripheral lymphocytes

ASJC Scopus subject areas

  • Medicine(all)

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