Efficacy of CD4/CD8 ratio of peripheral lymphocytes as a prognostic factor in severely handicapped people with mental retardation

Masamune Higashigawa; Toshiya Kamiya; Chizuko Nakano; Masako Kubo; Hajime Kawasaki; Kazuo Higuchi; Hirohito Kita; Toshiaki Ihara; Hitoshi Kamiya; Minoru Sakurai

doi:10.11261/iryo1946.45.651

Efficacy of CD4/CD8 ratio of peripheral lymphocytes as a prognostic factor in severely handicapped people with mental retardation

Masamune Higashigawa, Toshiya Kamiya, Chizuko Nakano, Masako Kubo, Hajime Kawasaki, Kazuo Higuchi, Hirohito Kita, Toshiaki Ihara, Hitoshi Kamiya, Minoru Sakurai

Allergic Diseases

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Abstract

We assessed the efficacy of CD4/CD8 ratio of the peripheral lymphocytes as a prognostic factor in 25 severely handicapped subjects with mental retardation, who were admitted to Suzuka Byoin National Sanatorium. The patients were divided into two groups; Group A (CD4/CD8<1, 12 patients) and Croup B (CD4/CD8>1, 13 patients). Three-year follow-up study revealed that six patients beloging to the Group A died but all patients belonging to the Group B survived. These data suggest that the CD4/CD8 ratio of peripheral lymphocytes might be one of the beneficial prognostic factors in severely handicapped subjects with mental retardation.

Original language	English (US)
Pages (from-to)	651-655
Number of pages	5
Journal	Japanese Journal of National Medical Services
Volume	45
Issue number	7
DOIs	https://doi.org/10.11261/iryo1946.45.651
State	Published - Jul 1991

Keywords

CD4/CD8 ratio
prognostic factor
severely handicapped subjects
surface marker of peripheral lymphocytes

ASJC Scopus subject areas

Medicine(all)

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10.11261/iryo1946.45.651

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title = "Efficacy of CD4/CD8 ratio of peripheral lymphocytes as a prognostic factor in severely handicapped people with mental retardation",

abstract = "We assessed the efficacy of CD4/CD8 ratio of the peripheral lymphocytes as a prognostic factor in 25 severely handicapped subjects with mental retardation, who were admitted to Suzuka Byoin National Sanatorium. The patients were divided into two groups; Group A (CD4/CD8<1, 12 patients) and Croup B (CD4/CD8>1, 13 patients). Three-year follow-up study revealed that six patients beloging to the Group A died but all patients belonging to the Group B survived. These data suggest that the CD4/CD8 ratio of peripheral lymphocytes might be one of the beneficial prognostic factors in severely handicapped subjects with mental retardation.",

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author = "Masamune Higashigawa and Toshiya Kamiya and Chizuko Nakano and Masako Kubo and Hajime Kawasaki and Kazuo Higuchi and Hirohito Kita and Toshiaki Ihara and Hitoshi Kamiya and Minoru Sakurai",

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AU - Higashigawa, Masamune

AU - Kamiya, Toshiya

AU - Nakano, Chizuko

AU - Kubo, Masako

AU - Kawasaki, Hajime

AU - Higuchi, Kazuo

AU - Kita, Hirohito

AU - Ihara, Toshiaki

AU - Kamiya, Hitoshi

AU - Sakurai, Minoru

PY - 1991/7

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AB - We assessed the efficacy of CD4/CD8 ratio of the peripheral lymphocytes as a prognostic factor in 25 severely handicapped subjects with mental retardation, who were admitted to Suzuka Byoin National Sanatorium. The patients were divided into two groups; Group A (CD4/CD8<1, 12 patients) and Croup B (CD4/CD8>1, 13 patients). Three-year follow-up study revealed that six patients beloging to the Group A died but all patients belonging to the Group B survived. These data suggest that the CD4/CD8 ratio of peripheral lymphocytes might be one of the beneficial prognostic factors in severely handicapped subjects with mental retardation.

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KW - prognostic factor

KW - severely handicapped subjects

KW - surface marker of peripheral lymphocytes

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Efficacy of CD4/CD8 ratio of peripheral lymphocytes as a prognostic factor in severely handicapped people with mental retardation

Abstract

Keywords

ASJC Scopus subject areas

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