Abstract
Dysembryoplastic neuroepithelial tumor (DNET) is a benign glioneuronal neoplasm typically associated with intractable, partial complex seizures in children and young adults. The authors present a case in which a DNET in a 45-year-old male was accompanied by a so-called "calcifying pseudoneoplasm of the neural axis" (CPNA), a rare tumefactive lesion considered reactive in nature. An MRI scan of the brain revealed a right temporal lobe abnormality with characteristics of DNT but no apparent calcification. Histologically, it exhibited classic features of DNET and an overlying meningeal-based, partially ossified, chondrocalcific lesion morphologically characteristic of CPNA. The association of DNET and CPNA has not been previously reported. The literature relevant to these two seizure-associated lesions is reviewed.
Original language | English (US) |
---|---|
Pages (from-to) | 197-202 |
Number of pages | 6 |
Journal | Clinical Neuropathology |
Volume | 30 |
Issue number | 4 |
DOIs | |
State | Published - Oct 2011 |
Keywords
- Calcifying pseudotumor
- Collision tumor
- DNT
- Seizure
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Neurology
- Clinical Neurology