Doppler Echocardiography of 240 Normal Carpentier-Edwards Duraflex Porcine Mitral Bioprostheses: A Comprehensive Assessment Including Time Velocity Integral Ratio and Prosthesis Performance Index

Lori A. Blauwet, Joseph F. Malouf, Heidi M. Connolly, David O. Hodge, Katie N. Evans, Regina M. Herges, Thoralf M. Sundt, Fletcher A. Miller

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Normal Doppler-derived echocardiographic data for Carpentier-Edwards Duraflex (Edwards Lifesciences, Irvine, CA) porcine bioprosthesis function in the mitral position are limited to 2 small series that did not include all Doppler-derived variables. The purpose of this study was to provide a comprehensive Doppler echocardiographic assessment of normal Carpentier-Edwards Duraflex mitral bioprosthesis function in a large number of patients assessed in the early postoperative phase. All of the important Doppler-derived hemodynamic variables reported to date were used. All patients had either a mitral valve prosthesis time velocity integral to left ventricular outflow tract time velocity integral ratio < 3.9 or an E velocity < 2.8. The pressure half-time was < 130 msec in all patients. Nearly all patients (97%) had an E velocity < 2.8 msec and a mitral valve prosthesis time velocity integral to left ventricular outflow tract time velocity integral ratio < 3.9 regardless of bioprosthesis size, left ventricular function, heart rate, hemoglobin, or hematocrit. With increasing bioprosthesis size, effective orifice area significantly increased, whereas the prosthesis performance index significantly decreased.

Original languageEnglish (US)
Pages (from-to)388-393
Number of pages6
JournalJournal of the American Society of Echocardiography
Volume22
Issue number4
DOIs
StatePublished - Apr 2009

Keywords

  • Doppler
  • Mitral prosthesis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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