DNA sequence variation within vanA, vanB, vanC-1, and vanC-2/3 genes of clinical Enterococcus isolates

Robin Patel, Jim R. Uhl, Peggy Kohner, Marlene K. Hopkins, James M. Steckelberg, Bruce Kline, Franklin R. Cockerill

Research output: Contribution to journalArticle

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Abstract

We studied the DNA sequence variation of van genes of 34 isolates of Enterococcus spp. The isolates containing the vanB gene exhibited between 0 and 41 base pair changes per 801 bp studied when the vanB sequences were compared to that of the reference strain Enterococcus faecalis V583. The isolates carrying the vanC-2 gene exhibited between 0 and 23 base pair changes per 346 bp studied when the vanC-2 sequences were compared to that of the reference strain E. casseliflavus ATCC 25788. Little variation was noted in the vanA and vanC-1 genes.

Original languageEnglish (US)
Pages (from-to)202-205
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume42
Issue number1
StatePublished - Jan 1998

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Enterococcus
Base Pairing
Genes
Enterococcus faecalis

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

Patel, R., Uhl, J. R., Kohner, P., Hopkins, M. K., Steckelberg, J. M., Kline, B., & Cockerill, F. R. (1998). DNA sequence variation within vanA, vanB, vanC-1, and vanC-2/3 genes of clinical Enterococcus isolates. Antimicrobial Agents and Chemotherapy, 42(1), 202-205.

DNA sequence variation within vanA, vanB, vanC-1, and vanC-2/3 genes of clinical Enterococcus isolates. / Patel, Robin; Uhl, Jim R.; Kohner, Peggy; Hopkins, Marlene K.; Steckelberg, James M.; Kline, Bruce; Cockerill, Franklin R.

In: Antimicrobial Agents and Chemotherapy, Vol. 42, No. 1, 01.1998, p. 202-205.

Research output: Contribution to journalArticle

Patel, R, Uhl, JR, Kohner, P, Hopkins, MK, Steckelberg, JM, Kline, B & Cockerill, FR 1998, 'DNA sequence variation within vanA, vanB, vanC-1, and vanC-2/3 genes of clinical Enterococcus isolates', Antimicrobial Agents and Chemotherapy, vol. 42, no. 1, pp. 202-205.
Patel, Robin ; Uhl, Jim R. ; Kohner, Peggy ; Hopkins, Marlene K. ; Steckelberg, James M. ; Kline, Bruce ; Cockerill, Franklin R. / DNA sequence variation within vanA, vanB, vanC-1, and vanC-2/3 genes of clinical Enterococcus isolates. In: Antimicrobial Agents and Chemotherapy. 1998 ; Vol. 42, No. 1. pp. 202-205.
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