DNA sequence variation within vanA, vanB, vanC-1, and vanC-2/3 genes of clinical Enterococcus isolates

Robin Patel, Jim R. Uhl, Peggy Kohner, Marlene K. Hopkins, James M. Steckelberg, Bruce Kline, Franklin R. Cockerill

Research output: Contribution to journalArticle

65 Scopus citations

Abstract

We studied the DNA sequence variation of van genes of 34 isolates of Enterococcus spp. The isolates containing the vanB gene exhibited between 0 and 41 base pair changes per 801 bp studied when the vanB sequences were compared to that of the reference strain Enterococcus faecalis V583. The isolates carrying the vanC-2 gene exhibited between 0 and 23 base pair changes per 346 bp studied when the vanC-2 sequences were compared to that of the reference strain E. casseliflavus ATCC 25788. Little variation was noted in the vanA and vanC-1 genes.

Original languageEnglish (US)
Pages (from-to)202-205
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume42
Issue number1
DOIs
StatePublished - Jan 1998

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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