DiRA: Discriminative, Restorative, and Adversarial Learning for Self-supervised Medical Image Analysis

Fatemeh Haghighi, Mohammad Reza Hosseinzadeh Taher, Michael B. Gotway, Jianming Liang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Discriminative learning, restorative learning, and adversarial learning have proven beneficial for self-supervised learning schemes in computer vision and medical imaging. Existing efforts, however, omit their synergistic effects on each other in a ternary setup, which, we envision, can sig-nificantly benefit deep semantic representation learning. To realize this vision, we have developed DiRA, thefirstframework that unites discriminative, restorative, and adversarial learning in a unified manner to collaboratively glean complementary visual information from unlabeled medical images for fine-grained semantic representation learning. Our extensive experiments demonstrate that DiRA (1) encourages collaborative learning among three learning ingredients, resulting in more generalizable representation across organs, diseases, and modalities; (2) outperforms fully supervised ImageNet models and increases robustness in small data regimes, reducing annotation cost across multiple medical imaging applications; (3) learns fine-grained semantic representation, facilitating accurate lesion localization with only image-level annotation; and (4) enhances state-of-the-art restorative approaches, revealing that DiRA is a general mechanism for united representation learning. All code and pretrained models are available at https://github.com/JLiangLab/DiRA.

Original languageEnglish (US)
Title of host publicationProceedings - 2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition, CVPR 2022
PublisherIEEE Computer Society
Pages20792-20802
Number of pages11
ISBN (Electronic)9781665469463
DOIs
StatePublished - 2022
Event2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition, CVPR 2022 - New Orleans, United States
Duration: Jun 19 2022Jun 24 2022

Publication series

NameProceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition
Volume2022-June
ISSN (Print)1063-6919

Conference

Conference2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition, CVPR 2022
Country/TerritoryUnited States
CityNew Orleans
Period6/19/226/24/22

Keywords

  • biological and cell microscopy
  • Medical
  • Self-& semi-& meta- & unsupervised learning

ASJC Scopus subject areas

  • Software
  • Computer Vision and Pattern Recognition

Fingerprint

Dive into the research topics of 'DiRA: Discriminative, Restorative, and Adversarial Learning for Self-supervised Medical Image Analysis'. Together they form a unique fingerprint.

Cite this