Diffuse alveolar hemorrhage syndromes

Research output: Contribution to journalArticlepeer-review

140 Scopus citations

Abstract

Diffuse alveolar hemorrhage (DAH) is a rare yet serious and frequently life-threatening complication of a variety of conditions. DAH may result from coagulation disorders, inhaled toxins, or infections. Most cases of DAH are caused by capillaritis associated with systemic autoimmune diseases such as antineutrophil cytoplasmic antibodies-associated vasculitis, anti-glomerular basement membrane disease, and systemic lupus erythematosus. Early recognition is crucial, because the prompt institution of supportive measures and immunosuppressive therapy is required for survival. Our understanding of DAH and its management is largely empiric and based on small case series and individual reports, many dating back more than one decade. To provide the practicing specialist with a rational diagnostic and management approach to the patient with DAH, this review summarizes the most recent publications and salient information derived from older publications.

Original languageEnglish (US)
Pages (from-to)12-17
Number of pages6
JournalCurrent opinion in rheumatology
Volume13
Issue number1
DOIs
StatePublished - Jan 19 2001

ASJC Scopus subject areas

  • Rheumatology

Fingerprint Dive into the research topics of 'Diffuse alveolar hemorrhage syndromes'. Together they form a unique fingerprint.

Cite this