Differences in fatigue severity in a sample of adult cancer patients

Velda J. Gonzalez, Cindy Tofthagen, Xusheng Chen, Elsa Pedro, Leorey N. Saligan

Research output: Contribution to journalArticle

2 Scopus citations


Aims and objectives: To describe differences in fatigue severity in a sample of adult Puerto Rican patients during and postcancer treatments. Background: Hispanics, including Puerto Ricans, are an understudied population who are under-represented in clinical trials, especially in symptom research. Although symptom management is a clinical priority in oncology care, treatment-related differences in Puerto Rican cancer patients’ report of fatigue severity have not been well described. Design/Methods: A cross-sectional survey was conducted from data of self-report of 138 Puerto Rican patients during and postcancer treatments at two ambulatory facilities located in San Juan, Puerto Rico. Fatigue severity was assessed using the Fatigue subscale from the Functional Assessment of Cancer Therapy-Fatigue quality of life questionnaire Spanish version. Differences in fatigue severity across type of treatment (radiation therapy, chemotherapy, combined radiation chemotherapy and post-treatment) were evaluated using nonparametric (Kruskal–Wallis and Mann–Whitney test) statistical tests. Results: The majority of the participants had prostate (33%) and breast (32%) cancers and were receiving radiation therapy (43%) or chemotherapy (28%). The Kruskal–Wallis test showed that there was a statistically significant difference in fatigue scores between the different four treatment conditions, χ2(3) = 39.1, p =.001 with patients on combined radiation chemotherapy or chemotherapy alone experiencing more severe fatigue. Conclusions: Findings from the current study suggest that type of treatment is a key component of the symptom burden of fatigue among the Puerto Rican oncology population. Specially, patients receiving combined therapy or chemotherapy alone were at increased risk for experiencing severe fatigue, compared to radiation therapy and post-treatment patients. Relevance to clinical practice: With the worldwide increase in migration of Puerto Rican families, nurses need to recognise that type of treatment is a key component of the symptom burden of fatigue among the Puerto Rican population. The results of this study will improve understanding of treatment-related fatigue to identify therapeutic targets and improve quality of life of patients.

Original languageEnglish (US)
Pages (from-to)3345-3354
Number of pages10
JournalJournal of Clinical Nursing
Issue number17-18
StatePublished - Sep 1 2018
Externally publishedYes



  • cancer
  • fatigue
  • symptom perception

ASJC Scopus subject areas

  • Nursing(all)

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