Diagnosis and invasive management of carotid atherosclerotic stenosis

James F Meschia, Thomas G Brott, Robert W. Hobson

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Carotid atherosclerotic stenosis is a known risk factor for ischemic stroke. Methods for detecting stenosis and revascularization abound. The objective of this review was to summarize the evidence for diagnosing carotid artery stenosis and treating symptomatic or asymptomatic stenosis with endarterectomy or stenting. An Ovid MEDLINE search identified relevant original research published between 1990 and 2006. With acceptable surgical risk and patient life expectancy, carotid endarterectomy is clearly indicated for symptomatic stenosis of more than 70%. Carotid endarterectomy is also recommended for symptomatic stenosis of more than 50%, but the health impact is less compelling. The US Food and Drug Administration has approved several stents for a subset of patients with carotid stenosis. Randomized comparisons of endarterectomy vs stenting have been performed in average- and high-risk patients with asymptomatic and symptomatic carotid artery stenosis with mixed results.

Original languageEnglish (US)
Pages (from-to)851-858
Number of pages8
JournalMayo Clinic Proceedings
Volume82
Issue number7
DOIs
StatePublished - 2007

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Carotid Stenosis
Pathologic Constriction
Endarterectomy
Carotid Endarterectomy
United States Food and Drug Administration
Life Expectancy
MEDLINE
Stents
Stroke
Health
Research

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Diagnosis and invasive management of carotid atherosclerotic stenosis. / Meschia, James F; Brott, Thomas G; Hobson, Robert W.

In: Mayo Clinic Proceedings, Vol. 82, No. 7, 2007, p. 851-858.

Research output: Contribution to journalArticle

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