Development and screening of brain-targeted lipid-based nanoparticles with enhanced cell penetration and gene delivery properties

Engineering & Materials Science

• Biocompatibility 8%
• Brain 50%
• Cytotoxicity 10%
• Degradation 4%
• DNA 20%
• Gene therapy 11%
• Genes 58%
• Imaging techniques 5%
• Ligands 8%
• Lipids 81%
• Liposomes 100%
• Molecular recognition 11%
• Nanoparticles 60%
• Neuroglia 11%
• Nucleic acids 9%
• Particle size analysis 7%
• Peptides 44%
• Phospholipids 10%
• Proteins 18%
• Screening 56%
• Surface treatment 7%
• Zeta potential 9%

Medicine & Life Sciences

• Brain 29%
• cadherin 5 9%
• Cell-Penetrating Peptides 37%
• Coculture Techniques 6%
• DNA 11%
• Endocytosis 6%
• Gene Transfer Techniques 8%
• Genes 24%
• Genetic Therapy 6%
• HIV-1 5%
• In Vitro Techniques 11%
• Ligands 4%
• Lipids 40%
• Liposomes 60%
• Nanoparticles 54%
• Nervous System Diseases 6%
• Neuroglia 6%
• Nucleic Acids 6%
• Peptides 4%
• Phospholipids 6%
• Plasmids 16%
• Proteins 7%
• Therapeutics 1%
• Transfection 17%
• Transferrin 36%
• Transferrin Receptors 8%

Chemical Compounds

• Disorder 7%
• Dose 6%
• Haemolytic 9%
• Liposome 56%
• Molecular Recognition 8%
• Nanoparticle 30%
• Nucleic Acid 7%
• Particle Size Distribution 8%
• Pentapeptide 10%
• Peptide 15%
• Phospholipid 7%
• Protein 7%
• Surface 2%
• Surface Modification 7%
• Zeta Potential 7%