Development and calibration of a nanometer manipulation and measurement system for molecular biomechanical testing

Zong Ping Luo, Kai Nan An

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

An optical tweezers system has been adopted for molecular biomechanical testing. To achieve nanometer manipulation and measurement, the system was modified with a piezo-stage and an interferometer. A systematic calibration was then performed on the displacement resolution. The results revealed that the system has a nanometer resolution which is sufficient for the measurement of deformation and stiffness of single macro-molecules.

Original languageEnglish (US)
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Pages221-222
Number of pages2
Volume39
StatePublished - 1998

Fingerprint

Calibration
Optical tweezers
Testing
Interferometers
Macros
Stiffness
Molecules

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Luo, Z. P., & An, K. N. (1998). Development and calibration of a nanometer manipulation and measurement system for molecular biomechanical testing. In American Society of Mechanical Engineers, Bioengineering Division (Publication) BED (Vol. 39, pp. 221-222)

Development and calibration of a nanometer manipulation and measurement system for molecular biomechanical testing. / Luo, Zong Ping; An, Kai Nan.

American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Vol. 39 1998. p. 221-222.

Research output: Chapter in Book/Report/Conference proceedingChapter

Luo, ZP & An, KN 1998, Development and calibration of a nanometer manipulation and measurement system for molecular biomechanical testing. in American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. vol. 39, pp. 221-222.
Luo ZP, An KN. Development and calibration of a nanometer manipulation and measurement system for molecular biomechanical testing. In American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Vol. 39. 1998. p. 221-222
Luo, Zong Ping ; An, Kai Nan. / Development and calibration of a nanometer manipulation and measurement system for molecular biomechanical testing. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Vol. 39 1998. pp. 221-222
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