Abstract
An optical tweezers system has been adopted for molecular biomechanical testing. To achieve nanometer manipulation and measurement, the system was modified with a piezo-stage and an interferometer. A systematic calibration was then performed on the displacement resolution. The results revealed that the system has a nanometer resolution which is sufficient for the measurement of deformation and stiffness of single macro-molecules.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 221-222 |
| Number of pages | 2 |
| Journal | American Society of Mechanical Engineers, Bioengineering Division (Publication) BED |
| Volume | 39 |
| State | Published - 1998 |
ASJC Scopus subject areas
- General Engineering