Developing disease activity and response criteria in connective tissue disease-related interstitial lung disease

Lesley Ann Saketkoo, Eric Lawrence Matteson, Kevin K. Brown, James R. Seibold, Vibeke Strand

Research output: Contribution to journalArticle

9 Scopus citations


The interstitial lung diseases (ILD) are a group of heterogeneous diseases that exert significant morbidity and mortality in connective tissue diseases (CTD). There is no consensus on measures of disease activity or therapeutic responsiveness, which hampers effective drug development and regulatory evaluation of candidate therapies. The CTD-ILD Special Interest Group represents an international multidisciplinary effort to identify consensus on criteria to measure disease activity and therapeutic response in CTD-ILD. We summarize the design of the studies we are conducting and progress leading to the OMERACT 10 and 2010 EULAR meetings.

Original languageEnglish (US)
Pages (from-to)1514-1518
Number of pages5
JournalJournal of Rheumatology
Issue number7
StatePublished - Jul 2011



  • Inflammatory myopathy
  • Interstitial lung disease
  • Outcome measures
  • Response criteria
  • Rheumatoid arthritis
  • Scleroderma

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy

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