Dementia treatment

Bradley F Boeve, Adam L. Boxer

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Introduction There is reason for optimism about future treatment of the most common causes of dementia. Advances in understanding the molecular pathologies that underlie the most common causes of neurodegenerative dementia are rapidly being translated into new treatments. At the same time, basic investigations into the neurophysiology of synaptic transmission, neuronal growth, development and survival have identified new receptors, genes and intracellular second messenger cascades that may serve as targets for new treatments for dementia. Whereas most currently approved medications that are used to treat dementia are effective only in ameliorating the symptoms of disease, in the near future, medications that modify the course of the disease by protecting the brain from dementia-related pathology may be available. New diagnostic tests will also help to identify accurately who is likely to benefit from such treatment and monitor their treatment response. This chapter will review the currently available treatments for the most common forms of dementia, focusing on clinical syndromes that are readily identifiable by practicing clinicians, as well as new treatments that are currently under investigation or new avenues for treatment suggested by recent advances in understanding the molecular pathologies of these disorders.

Original languageEnglish (US)
Title of host publicationThe Behavioral Neurology of Dementia
PublisherCambridge University Press
Pages213-253
Number of pages41
Volume9780521853958
ISBN (Print)9780511581410, 9780521853958
DOIs
StatePublished - Jan 1 2009

Fingerprint

Dementia
Molecular Pathology
Therapeutics
Neurophysiology
Brain Diseases
Second Messenger Systems
Growth and Development
Routine Diagnostic Tests
Synaptic Transmission
Pathology
Genes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Boeve, B. F., & Boxer, A. L. (2009). Dementia treatment. In The Behavioral Neurology of Dementia (Vol. 9780521853958, pp. 213-253). Cambridge University Press. https://doi.org/10.1017/CBO9780511581410.016

Dementia treatment. / Boeve, Bradley F; Boxer, Adam L.

The Behavioral Neurology of Dementia. Vol. 9780521853958 Cambridge University Press, 2009. p. 213-253.

Research output: Chapter in Book/Report/Conference proceedingChapter

Boeve, BF & Boxer, AL 2009, Dementia treatment. in The Behavioral Neurology of Dementia. vol. 9780521853958, Cambridge University Press, pp. 213-253. https://doi.org/10.1017/CBO9780511581410.016
Boeve BF, Boxer AL. Dementia treatment. In The Behavioral Neurology of Dementia. Vol. 9780521853958. Cambridge University Press. 2009. p. 213-253 https://doi.org/10.1017/CBO9780511581410.016
Boeve, Bradley F ; Boxer, Adam L. / Dementia treatment. The Behavioral Neurology of Dementia. Vol. 9780521853958 Cambridge University Press, 2009. pp. 213-253
@inbook{a30195cea2854554b49e020454c7f4c6,
title = "Dementia treatment",
abstract = "Introduction There is reason for optimism about future treatment of the most common causes of dementia. Advances in understanding the molecular pathologies that underlie the most common causes of neurodegenerative dementia are rapidly being translated into new treatments. At the same time, basic investigations into the neurophysiology of synaptic transmission, neuronal growth, development and survival have identified new receptors, genes and intracellular second messenger cascades that may serve as targets for new treatments for dementia. Whereas most currently approved medications that are used to treat dementia are effective only in ameliorating the symptoms of disease, in the near future, medications that modify the course of the disease by protecting the brain from dementia-related pathology may be available. New diagnostic tests will also help to identify accurately who is likely to benefit from such treatment and monitor their treatment response. This chapter will review the currently available treatments for the most common forms of dementia, focusing on clinical syndromes that are readily identifiable by practicing clinicians, as well as new treatments that are currently under investigation or new avenues for treatment suggested by recent advances in understanding the molecular pathologies of these disorders.",
author = "Boeve, {Bradley F} and Boxer, {Adam L.}",
year = "2009",
month = "1",
day = "1",
doi = "10.1017/CBO9780511581410.016",
language = "English (US)",
isbn = "9780511581410",
volume = "9780521853958",
pages = "213--253",
booktitle = "The Behavioral Neurology of Dementia",
publisher = "Cambridge University Press",

}

TY - CHAP

T1 - Dementia treatment

AU - Boeve, Bradley F

AU - Boxer, Adam L.

PY - 2009/1/1

Y1 - 2009/1/1

N2 - Introduction There is reason for optimism about future treatment of the most common causes of dementia. Advances in understanding the molecular pathologies that underlie the most common causes of neurodegenerative dementia are rapidly being translated into new treatments. At the same time, basic investigations into the neurophysiology of synaptic transmission, neuronal growth, development and survival have identified new receptors, genes and intracellular second messenger cascades that may serve as targets for new treatments for dementia. Whereas most currently approved medications that are used to treat dementia are effective only in ameliorating the symptoms of disease, in the near future, medications that modify the course of the disease by protecting the brain from dementia-related pathology may be available. New diagnostic tests will also help to identify accurately who is likely to benefit from such treatment and monitor their treatment response. This chapter will review the currently available treatments for the most common forms of dementia, focusing on clinical syndromes that are readily identifiable by practicing clinicians, as well as new treatments that are currently under investigation or new avenues for treatment suggested by recent advances in understanding the molecular pathologies of these disorders.

AB - Introduction There is reason for optimism about future treatment of the most common causes of dementia. Advances in understanding the molecular pathologies that underlie the most common causes of neurodegenerative dementia are rapidly being translated into new treatments. At the same time, basic investigations into the neurophysiology of synaptic transmission, neuronal growth, development and survival have identified new receptors, genes and intracellular second messenger cascades that may serve as targets for new treatments for dementia. Whereas most currently approved medications that are used to treat dementia are effective only in ameliorating the symptoms of disease, in the near future, medications that modify the course of the disease by protecting the brain from dementia-related pathology may be available. New diagnostic tests will also help to identify accurately who is likely to benefit from such treatment and monitor their treatment response. This chapter will review the currently available treatments for the most common forms of dementia, focusing on clinical syndromes that are readily identifiable by practicing clinicians, as well as new treatments that are currently under investigation or new avenues for treatment suggested by recent advances in understanding the molecular pathologies of these disorders.

UR - http://www.scopus.com/inward/record.url?scp=84927008790&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84927008790&partnerID=8YFLogxK

U2 - 10.1017/CBO9780511581410.016

DO - 10.1017/CBO9780511581410.016

M3 - Chapter

SN - 9780511581410

SN - 9780521853958

VL - 9780521853958

SP - 213

EP - 253

BT - The Behavioral Neurology of Dementia

PB - Cambridge University Press

ER -