Dementia treatment

Bradley F Boeve, Adam L. Boxer

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Introduction There is reason for optimism about future treatment of the most common causes of dementia. Advances in understanding the molecular pathologies that underlie the most common causes of neurodegenerative dementia are rapidly being translated into new treatments. At the same time, basic investigations into the neurophysiology of synaptic transmission, neuronal growth, development and survival have identified new receptors, genes and intracellular second messenger cascades that may serve as targets for new treatments for dementia. Whereas most currently approved medications that are used to treat dementia are effective only in ameliorating the symptoms of disease, in the near future, medications that modify the course of the disease by protecting the brain from dementia-related pathology may be available. New diagnostic tests will also help to identify accurately who is likely to benefit from such treatment and monitor their treatment response. This chapter will review the currently available treatments for the most common forms of dementia, focusing on clinical syndromes that are readily identifiable by practicing clinicians, as well as new treatments that are currently under investigation or new avenues for treatment suggested by recent advances in understanding the molecular pathologies of these disorders.

Original languageEnglish (US)
Title of host publicationThe Behavioral Neurology of Dementia
PublisherCambridge University Press
Pages213-253
Number of pages41
Volume9780521853958
ISBN (Print)9780511581410, 9780521853958
DOIs
StatePublished - Jan 1 2009

ASJC Scopus subject areas

  • Medicine(all)

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    Boeve, B. F., & Boxer, A. L. (2009). Dementia treatment. In The Behavioral Neurology of Dementia (Vol. 9780521853958, pp. 213-253). Cambridge University Press. https://doi.org/10.1017/CBO9780511581410.016