Degenerative mitral valve regurgitation: Understanding basic concepts and new developments

Hector I. Michelena, Yan Topilsky, Rakesh Suri, Maurice Enriquez-Sarano

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Chronic degenerative mitral regurgitation is the most common valvular disease in the United States. The objective of this RE article is to impart a balanced understanding of the basic concepts and new developments in assessment and management of patients with severe degenerative mitral regurgitation. Etiologic, epidemiologic, pathologic, and physiopathologic concepts are discussed, as well as the importance of surgical mitral valve repair as the current gold standard treatment. Research efforts in "decoding" the natural history and prognosis of patients with severe degenerative mitral regurgitation have produced important insights into the surgical timing of patients with asymptomatic mitral regurgitation, and the concept of early restorative surgery has emerged.

Original languageEnglish (US)
Pages (from-to)56-69
Number of pages14
JournalPostgraduate medicine
Volume123
Issue number2
DOIs
StatePublished - Mar 1 2011

Keywords

  • Cardiovascular disease
  • Mitral regurgitation
  • Restorative surgery

ASJC Scopus subject areas

  • Medicine(all)

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