Defending against smallpox: a focus on vaccines

Emily A. Voigt, Richard B Kennedy, Gregory A. Poland

Research output: Contribution to journalReview article

11 Scopus citations

Abstract

Smallpox has shaped human history, from the earliest human civilizations well into the 20th century. With high mortality rates, rapid transmission, and serious long-term effects on survivors, smallpox was a much-feared disease. The eradication of smallpox represents an unprecedented medical victory for the lasting benefit of human health and prosperity. Concerns remain, however, about the development and use of the smallpox virus as a biological weapon, which necessitates the need for continued vaccine development. Smallpox vaccine development is thus a much-reviewed topic of high interest. This review focuses on the current state of smallpox vaccines and their context in biodefense efforts.

Original languageEnglish (US)
Pages (from-to)1197-1211
Number of pages15
JournalExpert Review of Vaccines
Volume15
Issue number9
DOIs
StatePublished - Sep 1 2016

Keywords

  • biological warfare
  • bioterrorism
  • Smallpox
  • smallpox vaccine
  • vaccinia virus

ASJC Scopus subject areas

  • Immunology
  • Molecular Medicine
  • Pharmacology
  • Drug Discovery

Fingerprint Dive into the research topics of 'Defending against smallpox: a focus on vaccines'. Together they form a unique fingerprint.

  • Cite this